Indian birthwort
Aristolochia indica · Accepted scientific name
Scientific literature: Sparse (54 studies) · ★★☆☆☆
Indian birthwort, scientifically known as Aristolochia indica, is a perennial herbaceous plant native to East Asia. Characterized by its distinctive heart-shaped leaves and tubular flowers, it holds historical significance in traditional medicine. However, modern research warns of its potent nephrotoxicity, cautioning against its use due to severe health risks.
- Family
- Aristolochiaceae
- Native range
- Asia-Tropical
- Parts used
- Root · Leaf
- Common names
- Indian Birthwort · Indian Dutchman'S Pipe
- Scientific synonyms
- Aristolochia Indica Var. Lanceolata · Aristolochia Indica Var. Oxyphylla · 3 more
Names and Synonyms
Common Names
- Indian birthwort
- Indian Dutchman's pipe
Scientific Names
Accepted name
Aristolochia indicaSynonyms
- Aristolochia indica var. lanceolata
- Aristolochia indica var. oxyphylla
- Aristolochia indica var. magna
- Aristolochia lanceolata
- Aristolochia maysorensis
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Piperales, it is classified under the family Aristolochiaceae. Specifically, it is identified by the genus Aristolochia.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Piperales |
| Family | Aristolochiaceae |
| Genus | Aristolochia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant, Aristolochia indica, exhibits a widespread distribution across the diverse landscapes of the Indian Subcontinent. It is commonly found growing within the various regions of India. Its presence extends further into the neighboring territories of Bangladesh and Nepal. Additionally, the species can be located within the lush environments of Assam. Finally, its range encompasses the high-altitude terrains of the East Himalaya.
| Region | Area |
|---|---|
| Indian Subcontinent | Assam |
| Indian Subcontinent | Bangladesh |
| Indian Subcontinent | East Himalaya |
| Indian Subcontinent | India |
| Indian Subcontinent | Nepal |
| Indian Subcontinent | Sri Lanka |
| Indo-China | Andaman Is. |
| Indo-China | Myanmar |
| Australia | Northern Territory |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Aristolochia indica is characterized by its status as a perennial plant, allowing it to persist in its environment through multiple growing seasons. As a perennial herb, it maintains a continuous presence in its habitat, often developing robust rhizomatous or root systems that enable it to survive periods of dormancy and regrow annually. This long-term growth strategy allows the plant to establish a stable footprint within its ecological niche, transitioning through various stages of vegetative development and seasonal flowering cycles over several years.
- Lifecycle :
- perennial
Morphology
The morphology of Aristolochia indica is characterized by its growth form as a herb and a climbing plant, specifically functioning as an obligatory climber. It is a terrestrial species, existing in non-aquatic environments, and it maintains an independent life cycle as it is not a parasite. Regarding its structural composition, the plant exhibits variable woodiness, allowing it to adapt its physical support and stem structure as it climbs through its habitat.
- Aquatic :
- terrestrial
- Climber :
- obligatory
- Epiphyte :
- terrestrial
- Growth form :
- herb
- Parasite :
- independent
- Woodiness :
- variable
Sources: Global Inventory of Floras and Traits (GIFT)
Plant Parts
Aristolochia indica has 2 reported plant parts identified across 7 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 4 supporting sources | ★★☆☆☆ |
| Leaf | 3 supporting sources | ★★☆☆☆ |
Root
- PloS one
- Journal of ethnopharmacology
- Journal of natural products
- Ancient science of life
Leaf
- Journal of animal physiology and animal nutrition
- Journal of ethnopharmacology
- Parasitology research
Chemicals
Aristolochia indica has 13 reported phytochemicals identified across 7 scientific publications and several other databases. The most consistently reported chemicals include Aristolochic acid I, Tannins, Aristolic acid, Aristolindiquinone, Aristolochic acid.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Aristolochic acid I | 2 supporting sources | ★☆☆☆☆ |
| Tannins | 2 supporting sources | ★☆☆☆☆ |
| Aristolic acid | 1 supporting sources | ★☆☆☆☆ |
| Aristolindiquinone | 1 supporting sources | ★☆☆☆☆ |
| Aristolochic acid | 1 supporting sources | ★☆☆☆☆ |
| Aristolochic acid II | 1 supporting sources | ★☆☆☆☆ |
| CHLOROFORM | 1 supporting sources | ★☆☆☆☆ |
| Cepharadione A | 1 supporting sources | ★☆☆☆☆ |
| EA1 | 1 supporting sources | ★☆☆☆☆ |
| HEXANE | 1 supporting sources | ★☆☆☆☆ |
Aristolochic acid I
- Journal of ethnopharmacology
- Journal of natural products
Tannins
- Journal of animal physiology and animal nutrition
- Indian journal of pharmaceutical sciences
Aristolic acid
- Journal of natural products
Aristolindiquinone
- Journal of natural products
Aristolochic acid
- Journal of ethnopharmacology
Aristolochic acid II
- Journal of ethnopharmacology
CHLOROFORM
- Ancient science of life
Cepharadione A
- Journal of ethnopharmacology
EA1
- Evidence-based complementary and alternative medicine : eCAM
HEXANE
- Ancient science of life
Activities
Aristolochia indica has 11 reported activities identified across 7 scientific publications and several other databases. The most consistently reported activities include Abortifacient, Antibacterial, Antioxidant, Cytotoxic, Antifungal.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Abortifacient | 2 supporting sources | ★☆☆☆☆ |
| Antibacterial | 2 supporting sources | ★☆☆☆☆ |
| Antioxidant | 2 supporting sources | ★☆☆☆☆ |
| Cytotoxic | 2 supporting sources | ★☆☆☆☆ |
| Antifungal | 1 supporting sources | ★☆☆☆☆ |
| Antimicrobial | 1 supporting sources | ★☆☆☆☆ |
| Antivenom | 1 supporting sources | ★☆☆☆☆ |
| Fibrinolytic | 1 supporting sources | ★☆☆☆☆ |
| Repellent | 1 supporting sources | ★☆☆☆☆ |
| Teratogenic | 1 supporting sources | ★☆☆☆☆ |
Abortifacient
- Journal of ethnopharmacology
- Phytotherapy research : PTR
Antibacterial
- Ancient science of life
- BMC complementary and alternative medicine
Antioxidant
- Journal of ethnopharmacology
- Evidence-based complementary and alternative medicine : eCAM
Cytotoxic
- Journal of ethnopharmacology
- BMC complementary and alternative medicine
Antifungal
- BMC complementary and alternative medicine
Antimicrobial
- Journal of ethnopharmacology
Antivenom
- Evidence-based complementary and alternative medicine : eCAM
Fibrinolytic
- PloS one
Repellent
- Parasitology research
Teratogenic
- Phytotherapy research : PTR
Conditions
Aristolochia indica has 15 reported investigations on conditions identified across 7 scientific publications and several other databases. The most consistently reported conditions include Alzheimer's disease, Cerebrovascular Diseases, Plasmodium falciparum, dyspepsia, fertility.
| Condition | Supporting sources | Consensus |
|---|---|---|
| Alzheimer's disease | 1 supporting sources | ★☆☆☆☆ |
| Cerebrovascular diseases | 1 supporting sources | ★☆☆☆☆ |
| Plasmodium falciparum | 1 supporting sources | ★☆☆☆☆ |
| Dyspepsia | 1 supporting sources | ★☆☆☆☆ |
| Fertility | 1 supporting sources | ★☆☆☆☆ |
| Fever | 1 supporting sources | ★☆☆☆☆ |
| Infections | 1 supporting sources | ★☆☆☆☆ |
| Leishmaniasis | 1 supporting sources | ★☆☆☆☆ |
| Leprosy | 1 supporting sources | ★☆☆☆☆ |
| Malaria | 1 supporting sources | ★☆☆☆☆ |
Alzheimer's disease
- ACS omega
Cerebrovascular diseases
- PloS one
Plasmodium falciparum
- Parasitology research
Dyspepsia
- Journal of ethnopharmacology
Fertility
- Journal of natural products
Fever
- Journal of ethnopharmacology
Infections
- Journal of ethnopharmacology
Leishmaniasis
- Journal of ethnopharmacology
Leprosy
- Journal of ethnopharmacology
Malaria
- Parasitology research
Preparations
Aristolochia indica has 13 reported preparations identified across 7 scientific publications and several other databases. The most consistently reported preparations include leaves, Aqueous extract, Root water extracts, Roots, aqueous extract.
| Preparation | Supporting sources | Consensus |
|---|---|---|
| Leaves | 2 supporting sources | ★☆☆☆☆ |
| Aqueous extract | 1 supporting sources | ★☆☆☆☆ |
| Root water extracts | 1 supporting sources | ★☆☆☆☆ |
| Roots | 1 supporting sources | ★☆☆☆☆ |
| Aqueous extract | 1 supporting sources | ★☆☆☆☆ |
| Chloroform extract | 1 supporting sources | ★☆☆☆☆ |
| Crude extracts | 1 supporting sources | ★☆☆☆☆ |
| Ethanol extract | 1 supporting sources | ★☆☆☆☆ |
| Hexane extract | 1 supporting sources | ★☆☆☆☆ |
| Leaf extracts | 1 supporting sources | ★☆☆☆☆ |
Leaves
- Journal of animal physiology and animal nutrition
- Journal of ethnopharmacology
Aqueous extract
- Indian journal of pharmaceutical sciences
Root water extracts
- PloS one
Roots
- Journal of ethnopharmacology
Aqueous extract
- Ancient science of life
Chloroform extract
- Ancient science of life
Crude extracts
- Journal of ethnopharmacology
Ethanol extract
- Indian journal of pharmaceutical sciences
Hexane extract
- Ancient science of life
Leaf extracts
- Parasitology research