Indian birthwort

Aristolochia indica · Accepted scientific name

Scientific literature: Sparse (54 studies) · ★★☆☆☆

Indian birthwort, scientifically known as Aristolochia indica, is a perennial herbaceous plant native to East Asia. Characterized by its distinctive heart-shaped leaves and tubular flowers, it holds historical significance in traditional medicine. However, modern research warns of its potent nephrotoxicity, cautioning against its use due to severe health risks.

Family
Aristolochiaceae
Native range
Asia-Tropical
Parts used
Root · Leaf
Common names
Indian Birthwort · Indian Dutchman'S Pipe
Scientific synonyms
Aristolochia Indica Var. Lanceolata · Aristolochia Indica Var. Oxyphylla · 3 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Aristolochia indica

Synonyms

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Piperales, it is classified under the family Aristolochiaceae. Specifically, it is identified by the genus Aristolochia.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Piperales
Family Aristolochiaceae
Genus Aristolochia

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant, Aristolochia indica, exhibits a widespread distribution across the diverse landscapes of the Indian Subcontinent. It is commonly found growing within the various regions of India. Its presence extends further into the neighboring territories of Bangladesh and Nepal. Additionally, the species can be located within the lush environments of Assam. Finally, its range encompasses the high-altitude terrains of the East Himalaya.

Region Area
Indian Subcontinent Assam
Indian Subcontinent Bangladesh
Indian Subcontinent East Himalaya
Indian Subcontinent India
Indian Subcontinent Nepal
Indian Subcontinent Sri Lanka
Indo-China Andaman Is.
Indo-China Myanmar
Australia Northern Territory

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Aristolochia indica is characterized by its status as a perennial plant, allowing it to persist in its environment through multiple growing seasons. As a perennial herb, it maintains a continuous presence in its habitat, often developing robust rhizomatous or root systems that enable it to survive periods of dormancy and regrow annually. This long-term growth strategy allows the plant to establish a stable footprint within its ecological niche, transitioning through various stages of vegetative development and seasonal flowering cycles over several years.

Lifecycle :
perennial

Morphology

The morphology of Aristolochia indica is characterized by its growth form as a herb and a climbing plant, specifically functioning as an obligatory climber. It is a terrestrial species, existing in non-aquatic environments, and it maintains an independent life cycle as it is not a parasite. Regarding its structural composition, the plant exhibits variable woodiness, allowing it to adapt its physical support and stem structure as it climbs through its habitat.

Aquatic :
terrestrial
Climber :
obligatory
Epiphyte :
terrestrial
Growth form :
herb
Parasite :
independent
Woodiness :
variable

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Aristolochia indica has 2 reported plant parts identified across 7 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, leaf.

Plant parts reported in Aristolochia indica
Plant part Supporting sources Consensus
Root 4 supporting sources ★★☆☆☆
Leaf 3 supporting sources ★★☆☆☆

Root

  1. PloS one
  2. Journal of ethnopharmacology
  3. Journal of natural products
  4. Ancient science of life

Leaf

  1. Journal of animal physiology and animal nutrition
  2. Journal of ethnopharmacology
  3. Parasitology research

Chemicals

Aristolochia indica has 13 reported phytochemicals identified across 7 scientific publications and several other databases. The most consistently reported chemicals include Aristolochic acid I, Tannins, Aristolic acid, Aristolindiquinone, Aristolochic acid.

Chemicals reported in Aristolochia indica
Chemical Supporting sources Consensus
Aristolochic acid I 2 supporting sources ★☆☆☆☆
Tannins 2 supporting sources ★☆☆☆☆
Aristolic acid 1 supporting sources ★☆☆☆☆
Aristolindiquinone 1 supporting sources ★☆☆☆☆
Aristolochic acid 1 supporting sources ★☆☆☆☆
Aristolochic acid II 1 supporting sources ★☆☆☆☆
CHLOROFORM 1 supporting sources ★☆☆☆☆
Cepharadione A 1 supporting sources ★☆☆☆☆
EA1 1 supporting sources ★☆☆☆☆
HEXANE 1 supporting sources ★☆☆☆☆

Aristolochic acid I

  1. Journal of ethnopharmacology
  2. Journal of natural products

Tannins

  1. Journal of animal physiology and animal nutrition
  2. Indian journal of pharmaceutical sciences

Aristolic acid

  1. Journal of natural products

Aristolindiquinone

  1. Journal of natural products

Aristolochic acid

  1. Journal of ethnopharmacology

Aristolochic acid II

  1. Journal of ethnopharmacology

CHLOROFORM

  1. Ancient science of life

Cepharadione A

  1. Journal of ethnopharmacology

EA1

  1. Evidence-based complementary and alternative medicine : eCAM

HEXANE

  1. Ancient science of life

Activities

Aristolochia indica has 11 reported activities identified across 7 scientific publications and several other databases. The most consistently reported activities include Abortifacient, Antibacterial, Antioxidant, Cytotoxic, Antifungal.

Activities reported in Aristolochia indica
Activity Supporting sources Consensus
Abortifacient 2 supporting sources ★☆☆☆☆
Antibacterial 2 supporting sources ★☆☆☆☆
Antioxidant 2 supporting sources ★☆☆☆☆
Cytotoxic 2 supporting sources ★☆☆☆☆
Antifungal 1 supporting sources ★☆☆☆☆
Antimicrobial 1 supporting sources ★☆☆☆☆
Antivenom 1 supporting sources ★☆☆☆☆
Fibrinolytic 1 supporting sources ★☆☆☆☆
Repellent 1 supporting sources ★☆☆☆☆
Teratogenic 1 supporting sources ★☆☆☆☆

Abortifacient

  1. Journal of ethnopharmacology
  2. Phytotherapy research : PTR

Antibacterial

  1. Ancient science of life
  2. BMC complementary and alternative medicine

Antioxidant

  1. Journal of ethnopharmacology
  2. Evidence-based complementary and alternative medicine : eCAM

Cytotoxic

  1. Journal of ethnopharmacology
  2. BMC complementary and alternative medicine

Antifungal

  1. BMC complementary and alternative medicine

Antimicrobial

  1. Journal of ethnopharmacology

Antivenom

  1. Evidence-based complementary and alternative medicine : eCAM

Fibrinolytic

  1. PloS one

Repellent

  1. Parasitology research

Teratogenic

  1. Phytotherapy research : PTR

Conditions

Aristolochia indica has 15 reported investigations on conditions identified across 7 scientific publications and several other databases. The most consistently reported conditions include Alzheimer's disease, Cerebrovascular Diseases, Plasmodium falciparum, dyspepsia, fertility.

Conditions investigated for Aristolochia indica
Condition Supporting sources Consensus
Alzheimer's disease 1 supporting sources ★☆☆☆☆
Cerebrovascular diseases 1 supporting sources ★☆☆☆☆
Plasmodium falciparum 1 supporting sources ★☆☆☆☆
Dyspepsia 1 supporting sources ★☆☆☆☆
Fertility 1 supporting sources ★☆☆☆☆
Fever 1 supporting sources ★☆☆☆☆
Infections 1 supporting sources ★☆☆☆☆
Leishmaniasis 1 supporting sources ★☆☆☆☆
Leprosy 1 supporting sources ★☆☆☆☆
Malaria 1 supporting sources ★☆☆☆☆

Alzheimer's disease

  1. ACS omega

Cerebrovascular diseases

  1. PloS one

Plasmodium falciparum

  1. Parasitology research

Dyspepsia

  1. Journal of ethnopharmacology

Fertility

  1. Journal of natural products

Fever

  1. Journal of ethnopharmacology

Infections

  1. Journal of ethnopharmacology

Leishmaniasis

  1. Journal of ethnopharmacology

Leprosy

  1. Journal of ethnopharmacology

Malaria

  1. Parasitology research

Preparations

Aristolochia indica has 13 reported preparations identified across 7 scientific publications and several other databases. The most consistently reported preparations include leaves, Aqueous extract, Root water extracts, Roots, aqueous extract.

Preparations reported for Aristolochia indica
Preparation Supporting sources Consensus
Leaves 2 supporting sources ★☆☆☆☆
Aqueous extract 1 supporting sources ★☆☆☆☆
Root water extracts 1 supporting sources ★☆☆☆☆
Roots 1 supporting sources ★☆☆☆☆
Aqueous extract 1 supporting sources ★☆☆☆☆
Chloroform extract 1 supporting sources ★☆☆☆☆
Crude extracts 1 supporting sources ★☆☆☆☆
Ethanol extract 1 supporting sources ★☆☆☆☆
Hexane extract 1 supporting sources ★☆☆☆☆
Leaf extracts 1 supporting sources ★☆☆☆☆

Leaves

  1. Journal of animal physiology and animal nutrition
  2. Journal of ethnopharmacology

Aqueous extract

  1. Indian journal of pharmaceutical sciences

Root water extracts

  1. PloS one

Roots

  1. Journal of ethnopharmacology

Aqueous extract

  1. Ancient science of life

Chloroform extract

  1. Ancient science of life

Crude extracts

  1. Journal of ethnopharmacology

Ethanol extract

  1. Indian journal of pharmaceutical sciences

Hexane extract

  1. Ancient science of life

Leaf extracts

  1. Parasitology research