Anoectochilus formosanus

What's the taxonomical classification of Anoectochilus formosanus?

Anoectochilus formosanus belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within the class Equisetopsida and the subclass Magnoliidae, it is positioned in the order Asparagales. This plant is a member of the family Orchidaceae, falling specifically under the genus Anoectochilus, with its unique designation being the species formosanus.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Asparagales
Family Orchidaceae
Genus Anoectochilus
Species formosanus
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Anoectochilus formosanus has small, fleshy, elliptical leaves that grow in a compact rosette and produce miniature, fragrant, pale pink to white flowers with a prominent, trilobed lip. The flowers feature a distinctive nectar spur at the base of the labellum and often display fine purple or reddish spotting on the sepals and petals. Each individual bloom is quite tiny, typically measuring only a few millimeters in diameter, yet they often appear in dense clusters. The plant's growth habit is characterized by short, creeping rhizomes that allow it to form thick mats on mossy rocks or tree bark. This morphology is specifically adapted to its epiphytic lifestyle in humid, subtropical environments.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to the subtropical and tropical regions of Taiwan, where it primarily grows in mountainous forest environments. It is specifically documented within the island's diverse ecosystems, often favoring shaded areas with high humidity. Beyond its primary home in Taiwan, certain botanical records suggest its presence in parts of Southeast Asia. The species thrives in elevations that provide consistent moisture and filtered sunlight. This localized distribution makes it a significant part of the regional orchid biodiversity.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires bright, filtered light and high humidity levels between 60 and 80 percent to thrive in a controlled environment.

Growers should use a well-draining substrate, such as a mixture of fine bark and sphagnum moss, to prevent root rot. Frequent watering is necessary to keep the media moist, but the orchid must be allowed to dry slightly between applications to mimic its natural habitat. Maintaining consistent air circulation around the foliage is vital for preventing fungal diseases.

These specific conditions ensure the plant develops healthy pseudobulbs and produces its characteristic fragrant blooms.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Anoectochilus formosanus is utilized medicinally through its leaves, roots, shoots, stems, and the whole plant. The leaves are frequently processed into teas or extracts to support metabolic health and cognitive function. Medicinal practitioners often harvest the roots and stems to create concentrated decoctions for their purported anti-inflammatory properties. Young shoots are sometimes incorporated into traditional dietary remedies to balance internal energy. By using the whole plant, practitioners aim to harness the complete spectrum of bioactive compounds available in the species.

According to a study published by "Molecules (Basel, Switzerland)", the medicinal orchid Anoectochilus formosanus contains major bioactive compounds including total flavonoid and gastrodin. These specific constituents are found within the leaf, the stem, and the whole plant. The study utilized the aluminum chloride colorimetric method and ultra performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) to determine these levels. The tetraploid version of the plant produced significantly higher contents of these compounds compared to the diploid. These results suggest that the tetraploid plants are suitable raw materials for the pharmaceutical industry.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaf
  • root
  • shoot
  • stem
  • whole plants
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant, Anoectochilus formosanus, has been utilized in Chinese folk medicine for centuries to treat various ailments and promote overall longevity. Practitioners often use the plant to address inflammatory conditions, boost the immune system, and support metabolic health. In many traditional practices, the leaves are prepared as a decoction or tea to aid in cooling the body and clearing heat. Historical records suggest its use was specifically focused on enhancing vital energy and improving blood circulation. This long-standing medicinal history highlights its significant cultural value within herbalist traditions.

According to a study published by "Journal of Zhejiang University. Science. B", Anoectochilus formosanus, commonly known as Jewel Orchid, is a rare and threatened medicinal Orchidaceae plant used in Chinese folk medicine. This plant is historically utilized to treat hypertension, diabetes, and heart disease. Its highly potent medicinal activity is attributed to secondary metabolites, specifically kinsenosides and flavonoids. The study observed that after 10 weeks of symbiotic cultivation with F-23 fungus, kinsenoside contents increased by 85.5%. Additionally, levels of isorhamnetin-3-O-β-D-rutinoside and isorhamnetin-3-O-β-D-glucopyranoside increased by 226.1% and 196.0%, respectively.

The hystorical systems that uses this plant are shown in the list below.

  • Chinese folk medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Anoectochilus formosanus?

This plant has anticancer, antitumor, detoxification, heat-clearing, and immunostimulating pharmacological activities. Its chemical constituents allow it to inhibit the growth of malignant cells and disrupt tumor progression. The plant also serves a vital role in detoxification processes by neutralizing harmful substances within the body. Furthermore, it possesses heat-clearing properties used in traditional medicine to reduce inflammation and fever. These combined effects contribute to a significant enhancement of the body's overall immune response.

According to a study published by "Journal of biomedical science", the herbal extract of Anoectochilus formosanus (AF) is a popular folk medicine with anticancer activity. The bioactivities of this plant extract were characterized in MCF-7 cancer cells using metabolite profiling and DNA microarray analysis of global gene expression profiles. When compared to the single-compound drug plumbagin, the AF extract showed a similar level of complexity in transcriptional regulation at the genomic level. This similarity was revealed by the number of up- or downregulated genes and by specific but distinct patterns found in the gene-clustering analysis.

The primary pharmacological activities of this plant are shown in the list below.

  • anticancer
  • antitumor
  • detoxification
  • heat-clearing
  • immunostimulating
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains several bioactive medicinal compounds including kinsenoside, specifically 3-(R)-3-beta-D-glucopyranosyloxybutanolide, corchoionoside C, flavonoids, and gastrodin. These various chemical constituents contribute to the diverse therapeutic properties attributed to the species. The presence of kinsenosides is particularly significant for its biological activities. Additionally, the flavonoids and gastrodin within the plant support its traditional medicinal uses. These specific compounds collectively define the pharmacological profile of Anoectochilus formosanus.

According to a study published by "Chemical & pharmaceuatl bulletin", the glycosidic constituents of whole plants of Anoectochilus formosanus propagated by tissue culture were investigated. One new compound identified was 2-(beta-D-glucopyranosyloxymethyl)-5-hydroxymethylfuran. The study also isolated the known compound 3-(R)-3-beta-D-glucopyranosyloxybutanolide, also known as kinsenoside. Other isolated substances include 3-(R)-3-beta-D-glucopyranosyloxy-4-hydroxybutanoic acid and 1-O-isopropyl-beta-D-glucopyranoside. Additionally, the research identified (R)-(+)-3,4-dihydroxy-butanoic acid y-lactone, 4-(beta-D-glucopyranosyloxy)benzyl alcohol, (6R,9S)-9-hydroxy-megastigma-4,7-dien-3-one-9-O-beta-glucopyranoside, and corchoionoside C.

The primary medicinal compounds of this plant are shown in the list below.

  • 3-(R)-3-beta-D-glucopyranosyloxybutanolide (kinsenoside)
  • corchoionoside C
  • gastrodin
  • kinsenosides
  • isorhamnetin-3-O-β-D-glucopyranoside
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for managing colon cancer, various human cancers, tumors, diabetes, and hypertension. Researchers study its bioactive compounds to determine how they might inhibit the growth of malignant cells. Specifically, its properties are investigated for their potential to reduce the size of a tumor in different medical models. The plant also shows promise in regulating blood sugar levels for those suffering from diabetes. Furthermore, its medicinal components may help in lowering blood pressure to treat hypertension.

According to a study published by "Phytomedicine : international journal of phytotherapy and phytopharmacology", the water extract of Anoectochilus formosanus Hayata showed potent tumor inhibitory activity in BALB/c mice after the transplantation of CT-26 murine colon cancer cells. Mice pre-administered with the plant for 2 days before transplantation and treated for 12 consecutive days showed tumor-inhibition ratios of 55.4% and 58.9% at oral doses of 50 and 10 mg/mouse per day. For tumor-bearing mice treated for 12 consecutive days, tumor inhibition ratios remained at 23.8% and 40.5% at doses of 50 and 10 mg/mouse. The plant may also activate immune responses by stimulating lymphoid tissue proliferation and activating the phagocytosis of peritoneal macrophages against Staphylococcus aureus. This suggests the antitumor activity of Anoectochilus formosanus may be linked to its potent immunostimulating effect.

The main health conditions this plant is used for are shown in the list below.

  • colon cancer
  • human cancers
  • tumor
  • diabetes
  • heart disease
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Anoectochilus formosanus, a species used in traditional medicine to create various medicinal herbal preparations such as herbal extracts, decoctions, and tinctures. These preparations often target physiological functions like boosting the immune system or improving metabolic health. The most common form is a concentrated herbal extract, which is frequently processed into powders or liquid supplements for easier consumption. Many practitioners also prepare decoctions by boiling the plant material in water to release its bioactive compounds. These diverse methods allow for different levels of potency and bioavailability in the final medicinal product.

According to a study published by "Journal of biomedical science", metabolite profiling and DNA microarray analysis were used to characterize the bioactivities of the herbal extract of Anoectochilus formosanus in MCF-7 cancer cells. This plant is a popular folk medicine with anticanceer activity. The pharmacogenomic activities of the Anoectochilus formosanus extract were compared to those of the single-compound drug, plumbagin. A similar level of complexity in transcriptional regulation at the genomic level was observed for both the Anoectochilus formosanus extract-treated and plumbagin-treated MCF-7 cells. This similarity was revealed by the number of up- or downregulated genes and by specific patterns found in the gene-clustering analysis.

The main herbal preparations of this plant are shown in the list below.

  • herbal extract
Evidence Level: ★★★☆☆

What side effects this plant can have?

This plant can demonstrate significant therapeutic potential through its documented anticancer activity and various medicinal properties. Research indicates that extracts from Anoectochilus formosanus contain bioactive compounds that inhibit the growth of specific cancer cell lines. These phytochemicals may help regulate cell cycle progression and induce apoptosis in malignant cells. Beyond its potential in oncology, the plant is frequently utilized in traditional medicine to support metabolic functions and reduce inflammation. However, more clinical studies are required to fully understand the long-term safety and precise physiological impact on humans.

According to a study published by "Journal of biomedical science", the herbal extract of Anoectochilus formosanus is a popular folk medicine with anticancer activity. Researchers used metabolite profiling and DNA microarray analysis of global gene expression profiles to characterize its bioactivities in MCF-7 cancer cells. The pharmacogenomic activities of this plant extract as a crude phytocompound mixture were compared to the single-compound drug, plumbagin. A similar level of complexity in transcriptional regulation at the genomic level was observed for both Anoectochilus formosanus extract-treated and plumbagin-treated MCF-7 cells. This was revealed by the number of up- or downregulated genes and by specific but distinct patterns found in the gene-clustering analysis.

The main side effects this plant can have are shown in the list below.

  • anticancer activity
Evidence Level: ★★★☆☆

What herbs are paired with Anoectochilus formosanus?

This plant Anoectochilus formosanus is traditionally paired with herbs such as ginger, dried tangerine peel, and licorice root to enhance its medicinal properties in traditional formulas.

These combinations are often utilized to balance the plant's inherent qualities and improve its effectiveness in treating respiratory ailments. Ginger is frequently included to warm the digestive system and counteract any potential coldness from the primary herb. Tangerine peel helps to regulate energy flow and clear phlegm when used alongside the orchid.

Together, these botanical pairings create a synergistic effect aimed at restoring internal equilibrium.

Evidence Level: ★☆☆☆☆