Ashitaba

Angelica keiskei · Accepted scientific name

Scientific literature: Sparse (63 studies) · ★★☆☆☆

Ashitaba, scientifically known as Angelica keiskei, is a revered medicinal herb native to the subtropical regions of Japan. Renowned for its potent bioactive compounds, it is traditionally utilized in East Asian medicine to support blood circulation, enhance vitality, and promote overall wellness through its unique antioxidant properties.

Family
Apiaceae
Native range
Asia-Temperate
Parts used
Stem · Leaf
Common names
Ashitaba
Scientific synonyms
Angelica Utilis · Angelica Keiskei F. Foliosa · 1 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Angelica keiskei

Synonyms

Regional and Traditional Names

French:

  • ashitaba

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta within the class Equisetopsida. Classified under the subclass Magnoliidae and the order Apiales, it is a member of the Apiaceae family. Ultimately, its taxonomic identity is defined by its placement in the genus Angelica.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Apiales
Family Apiaceae
Genus Angelica

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a highly localized geographical distribution within the natural landscapes of Eastern Asia. Specifically, its occurrence is restricted to the islands of Japan. Within this region, it thrives in unique habitats that support its specialized growth requirements. Because its range is so narrow, the species is considered an endemic element of the Japanese flora. Consequently, understanding its specific environmental needs is crucial for the conservation of this regional botanical treasure.

Region Area
Eastern Asia Japan

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Morphology

The morphology of Angelica keiiskei is characterized by its classification as a herb, exhibiting a growth form that lacks persistent structural support from secondary xylem. As a non-woody plant, it does not develop a true woody stem, instead maintaining a herbaceous structure throughout its life cycle.

Growth form :
herb
Woodiness :
non-woody

Sources: Global Inventory of Floras and Traits (GIFT)

Plant Parts

Angelica keiskei has 3 reported plant parts identified across 4 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include stem, leaf, root.

Plant parts reported in Angelica keiskei
Plant part Supporting sources Consensus
Stem 2 supporting sources ★☆☆☆☆
Leaf 1 supporting sources ★☆☆☆☆
Root 1 supporting sources ★☆☆☆☆

Stem

  1. Journal of natural products
  2. Evidence-based complementary and alternative medicine : eCAM

Leaf

  1. Evidence-based complementary and alternative medicine : eCAM

Root

  1. In vivo (Athens, Greece)

Chemicals

Angelica keiskei has 23 reported phytochemicals identified across 4 scientific publications and several other databases. The most consistently reported chemicals include 4-Hydroxyderricin, Xanthoangelol, Flavonoids, 3'-carboxymethyl-4,2'-dihydroxy-4'-methoxychalcone, 4'-O-Geranylnaringenin.

Chemicals reported in Angelica keiskei
Chemical Supporting sources Consensus
4-Hydroxyderricin 5 supporting sources ★★★☆☆
Xanthoangelol 4 supporting sources ★★☆☆☆
Flavonoids 3 supporting sources ★★☆☆☆
3'-carboxymethyl-4,2'-dihydroxy-4'-methoxychalcone 1 supporting sources ★☆☆☆☆
4'-O-Geranylnaringenin 1 supporting sources ★☆☆☆☆
7-hydroxycoumarin 1 supporting sources ★☆☆☆☆
BORNYL ACETATE 1 supporting sources ★☆☆☆☆
Coumarins 1 supporting sources ★☆☆☆☆
Diterpene 1 supporting sources ★☆☆☆☆
Galacturonic acid 1 supporting sources ★☆☆☆☆

4-Hydroxyderricin

  1. Planta medica
  2. Heliyon
  3. Archives of biochemistry and biophysics
  4. Nutrients
  5. Chemical & pharmaceutical bulletin

Xanthoangelol

  1. Planta medica
  2. Heliyon
  3. Archives of biochemistry and biophysics
  4. Chemical & pharmaceutical bulletin

Flavonoids

  1. Archives of pharmacal research
  2. Redox report : communications in free radical research
  3. Drug design, development and therapy

3'-carboxymethyl-4,2'-dihydroxy-4'-methoxychalcone

  1. Molecules (Basel, Switzerland)

4'-O-Geranylnaringenin

  1. Molecules (Basel, Switzerland)

7-hydroxycoumarin

  1. Natural products and bioprospecting

BORNYL ACETATE

  1. Natural products and bioprospecting

Coumarins

  1. Archives of pharmacal research

Diterpene

  1. Archives of pharmacal research

Galacturonic acid

  1. Natural product research

Activities

Angelica keiskei has 3 reported activities identified across 4 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Hepatoprotective, Vasorelaxant.

Activities reported in Angelica keiskei
Activity Supporting sources Consensus
Antioxidant 4 supporting sources ★★☆☆☆
Hepatoprotective 1 supporting sources ★☆☆☆☆
Vasorelaxant 1 supporting sources ★☆☆☆☆

Antioxidant

  1. Redox report : communications in free radical research
  2. Journal of photochemistry and photobiology. B, Biology
  3. Heliyon
  4. Drug design, development and therapy

Hepatoprotective

  1. Heliyon

Vasorelaxant

  1. Journal of photochemistry and photobiology. B, Biology

Conditions

Angelica keiskei has 16 reported investigations on conditions identified across 4 scientific publications and several other databases. The most consistently reported conditions include oxidative stress, COVID-19, Staphylococcus aureus, aging, cancer.

Conditions investigated for Angelica keiskei
Condition Supporting sources Consensus
Oxidative stress 3 supporting sources ★★☆☆☆
Covid-19 1 supporting sources ★☆☆☆☆
Staphylococcus aureus 1 supporting sources ★☆☆☆☆
Aging 1 supporting sources ★☆☆☆☆
Cancer 1 supporting sources ★☆☆☆☆
Dyschezia 1 supporting sources ★☆☆☆☆
Dysuria 1 supporting sources ★☆☆☆☆
Hypertension 1 supporting sources ★☆☆☆☆
Infertility 1 supporting sources ★☆☆☆☆
Inflammation 1 supporting sources ★☆☆☆☆

Oxidative stress

  1. Redox report : communications in free radical research
  2. Heliyon
  3. Natural product research

Covid-19

  1. Journal of integrative medicine

Staphylococcus aureus

  1. Planta medica

Aging

  1. Redox report : communications in free radical research

Cancer

  1. Journal of natural products

Dyschezia

  1. Archives of pharmacal research

Dysuria

  1. Archives of pharmacal research

Hypertension

  1. Archives of pharmacal research

Infertility

  1. Antioxidants (Basel, Switzerland)

Inflammation

  1. Archives of pharmacal research

Preparations

Angelica keiskei has 9 reported preparations identified across 4 scientific publications and several other databases. The most consistently reported preparations include ethyl acetate-soluble fraction, ethyl acetate-soluble fraction of exudates of the stems, health food, methanol extract, powder.

Preparations reported for Angelica keiskei
Preparation Supporting sources Consensus
Ethyl acetate-soluble fraction 1 supporting sources ★☆☆☆☆
Ethyl acetate-soluble fraction of exudates of the stems 1 supporting sources ★☆☆☆☆
Health food 1 supporting sources ★☆☆☆☆
Methanol extract 1 supporting sources ★☆☆☆☆
Powder 1 supporting sources ★☆☆☆☆
Powder from the sap 1 supporting sources ★☆☆☆☆
Roots 1 supporting sources ★☆☆☆☆
Standardized plant extract combination 1 supporting sources ★☆☆☆☆
Water extract 1 supporting sources ★☆☆☆☆

Ethyl acetate-soluble fraction

  1. Journal of natural products

Ethyl acetate-soluble fraction of exudates of the stems

  1. Journal of natural products

Health food

  1. Archives of pharmacal research

Methanol extract

  1. Journal of natural products

Powder

  1. Antioxidants (Basel, Switzerland)

Powder from the sap

  1. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association

Roots

  1. In vivo (Athens, Greece)

Standardized plant extract combination

  1. Journal of photochemistry and photobiology. B, Biology

Water extract

  1. Redox report : communications in free radical research