Amaranthus spinosus

What's the taxonomical classification of Amaranthus spinosus?

Amaranthus spinosus belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Moving through its specific hierarchy, the plant is a member of the order Caryophyllales and falls within the family Amaranthaceae. Finally, its taxonomic identity is completed by its placement in the genus Amaranthus, specifically as the species spinosus.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Caryophyllales
Family Amaranthaceae
Genus Amaranthus
Species spinosus
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Amaranthus spinosus has an erect, branched stem that typically reaches heights of 0.5 to 1.5 meters and is characterized by the presence of sharp, woody spines at the base of the leaf petioles. The leaves are alternate, ovate to lanceolate in shape, and possess entire margins with distinctively pointed tips. Its inflorescences consist of dense, greenish spikes that emerge from the leaf axils or the terminal ends of the branches. Small, inconspicuous flowers are arranged in these clusters and eventually produce tiny, black, kidney-shaped seeds. The entire plant structure is adapted for durability in disturbed soils and various environmental conditions.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to tropical and subtropical regions of Africa, Asia, and the Americas, but it has become naturalized in many other parts of the world. It is widely distributed across most of the continental United States and throughout much of Europe and Australia. Because it thrives in disturbed soils, it is frequently found along roadsides, in agricultural fields, and within urban waste areas. Its ability to adapt to various climates allows it to spread across diverse landscapes ranging from temperate zones to tropical environments. The species continues to expand its range globally due to its high seed production and resilience.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

Amaranthus spinosus contains medicinal properties found in its entire structure, specifically within the leaves, stems, roots, and seeds. The leaves are frequently prepared as a decoction or juice to treat inflammation and digestive issues. Its roots are often utilized in traditional medicine to manage fever and various skin ailments. The seeds can be consumed or processed to provide nutritional support and alleviate certain internal discomforts. Additionally, the stems are sometimes integrated into topical applications to address localized swelling.

Evidence Level: ★☆☆☆☆

What are the pharmacological activities of Amaranthus spinosus?

This plant has potent pharmacological activities including anti-diabetic, antibacterial, anticancer, antimalarial, and antioxidant properties. Its phytochemical constituents work to regulate blood glucose levels, making it a valuable subject for diabetes research. The presence of bioactive compounds also allows the plant to inhibit the growth of various pathogenic bacteria and combat malaria parasites. Additionally, its strong antioxidant capacity helps neutralize free radicals, which plays a crucial role in preventing cellular damage. Studies further suggest that its chemical profile may possess significant anticancer potential by interfering with tumor cell progression.

According to a study published by "Cellular and molecular biology (Noisy-le-Grand, France)", the ethanolic extract of Amaranthus spinosus leaves administered at doses of 150, 300 and 450 mg/kg bw demonstrates potential antidiaabetic activity. Among these doses, the higher doses significantly decreased plasma glucose levels (p<0.01 and p<0.001) and hepatic glucose-6-phophatase activity (p<0.01 and p<0.001) in type-1 and type-2 diabetic rats. These higher doses also increased hepatic glycogen content (p<0.01) and hexokinase activity (p<0.01 and p<0.001). Furthermore, the higher doses significantly lowered plasma and hepatic lipids, urea, creatinine levels (p<0.001) and lipid peroxidation. This process includes an improvement in the antioxidant profiles (p<0.001) of both type-1 and type-2 diabetic rats.

Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains a diverse array of medicinal compounds including rutin, alkaloids, betalains, glycosides, and terpenes. The presence of rutin, a potent flavonoid, provides significant antioxidant and anti-inflammatory benefits to the organism. Various alkaloids and glycosides within the plant contribute to its complex pharmacological profile and therapeutic potential. Additionally, the betalains act as natural pigments that offer cellular protection against oxidative stress. Finally, the terpenoids found in the leaves and stems play a crucial role in the plant's antimicrobial activities.

According to a study published by "Plants (Basel, Switzerland)", the plant Amaranthus spinosus contains bioactive compounds including phenolic and flavonoid compounds. Rutin was identified as the most abundant flavonoid compound in this species. The accumulation of these medicinal compounds is influenced by environmental factors such as heat stress at 40 °C under well-watered conditions. Additionally, combined drought and heat stress at 30 °C and 35 °C appeared to induce the accumulation of caffeic acid and rutin.

Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating anaemia, constipation, diabetes mellitus, jaundice, and various gut disorders. The leaves and roots are often prepared as decoctions to help increase red blood cell counts in patients suffering from blood deficiencies. Its natural properties are also utilized to regulate blood sugar levels and soothe digestive tract inflammation. Furthermore, the plant acts as a natural laxative to alleviate constipation and helps clear bile to assist in recovering from jaundice. These diverse applications demonstrate its significant role in traditional medicinal practices for managing multiple systemic issues.

According to a study published by "African journal of traditional, complementary, and alternative medicines : AJTCAM", Amaranthus spinosus is used in the ethnomedicine of Côte d'Ivoire for the treatment of anaemia. This plant was identified as one of the most promising among 30 recorded medicinal plants. It contained an iron content of 236.6 mg/100 g. These findings support its traditional use in managing anaemia in the Northern and South-Eastern regions of the country.

Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant can be prepared as a decoction by boiling the roots or stems in water to extract medicinal properties for internal use. An infusion made from the leaves is often consumed as a soothing tea to address various systemic ailments. For external skin irritations or wounds, a crushed leaf poultice can be applied directly to the affected area. The plant can also be processed into a tincture using alcohol to create a concentrated liquid extract for long-term storage. These different methods allow for the versatile application of its healing components in traditional medicine.

The main herbal preparations of this plant are shown in the list below.

  • Decoction
  • Infusion
  • Poultice
  • Tincture
Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause significant gastrointestinal distress and potential kidney issues due to the high concentration of oxalates found in its tissues. Ingesting the plant often leads to acute symptoms such as nausea and vomiting. Individuals may also experience painful stomach cramps and persistent diarrhea after consumption. The presence of these oxalates is the primary driver of the plant's toxicity. Therefore, caution is necessary to avoid these unpleasant physiological reactions.

The main side effects this plant can have are shown in the list below.

  • Toxicity from oxalates
  • Nausea
  • Vomiting
  • Diarrhea
  • Stomach cramps
Evidence Level: ★☆☆☆☆