Bitter aloe

Aloe ferox · Accepted scientific name

Scientific literature: Sparse (69 studies) · ★★☆☆☆

Bitter aloe, scientifically known as Aloe ferox, is a powerful medicinal succulent native to South Africa. Renowned for its intense bitterness, the plant's sap is traditionally harvested for its potent laxative properties. Beyond digestion, it is widely utilized in herbal medicine for its antimicrobial and anti-inflammatory therapeutic benefits.

Family
Asphodelaceae
Native range
Africa
Parts used
Leaf · Leaves
Common names
Cape Aloe · Bitter Aloe
Scientific synonyms
Aloe Galpinii · Pachidendron Pseudoferox · 11 more

Names

Common Names

Regional and Traditional Names

Spanish:

  • Aloe ferox var subferox
  • Aloe supralaevis var erythrocarpa
  • Aloe ferox var. galpinii
  • Aloe supralaevis var. erythrocarpa
  • Aloe supralaevis
  • Aloe ferox var incurva
  • Aloe candelabrum
  • Aloe perfoliata var ferox
  • Aloe ferox var. subferox
  • Busipho ferox
  • Aloe perfoliata var. ferox
  • Aloe ferox var. incurva
  • Aloe pseudoferox
  • Aloe galpinii
  • Aloe pallancae
  • Aloe subferox

French:

  • Aloès du Cap

Scientific Names

Accepted name

Aloe ferox

Synonyms

Taxonomical Classification

This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and class Equisetopsida. Within the subclass Magnoliidae, it is ordered under Asparagales and placed in the family Asphodelaceae. Finally, it is identified by the genus Aloe, specifically as the species Aloe ferox.

Rank Classification Source
Kingdom Plantae WCVP
Phylum Streptophyta WCVP
Class Equisetopsida WCVP
Subclass Magnoliidae WCVP
Order Asparagales WCVP
Family Asphodelaceae WCVP
Genus Aloe WCVP

Distribution

This plant is widely recognized for its presence within the diverse landscapes of Southern Africa. Its primary distribution can be found throughout the various Cape Provinces. Additionally, the species is known to inhabit the mountainous regions of Lesotho. It also grows naturally across the expansive plains of the Free State. Consequently, these specific areas define the core geographical range of Aloe ferox.

Region Area Source
Southern Africa Cape Provinces WCVP
Southern Africa Lesotho WCVP
Southern Africa Free State WCVP

Plant Parts

This plant, Aloe ferox, is a succulent known for its medicinal potency, which is primarily concentrated in its large, fleshy leaves. While the whole-leaf can be processed for various applications, the bitter yellow sap found within the leaf is the most sought-after component for its purgative properties. Unlike some other species, the roots are not typically the primary focus of medicinal extraction, nor are the seeds commonly used in traditional remedies. Instead, the medicinal value is most effectively derived from the thick, juice-filled leaves that characterize the plant's structure.
Plant Part Sources Confidence
leaf Journal of ethnopharmacology (and other 3 sources) ★★☆☆☆
leaves Journal of ethnopharmacology (and other 2 sources) ★☆☆☆☆
Leaves The Onderstepoort journal of veterinary research (and other 1 sources) ★☆☆☆☆
bulbs Frontiers in pharmacology (and other 1 sources) ★☆☆☆☆
gel Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
leaf exudate Planta medica (and other 1 sources) ★☆☆☆☆
roots Frontiers in pharmacology (and other 1 sources) ★☆☆☆☆
seeds Natural product communications (and other 1 sources) ★☆☆☆☆
whole-leaf Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆

Chemicals

Aloe ferox has 29 reported phytochemicals identified across 12 scientific publications and several other databases. The most consistently reported chemicals include Flavonoids, aloin, 5-Hydroxyaloin A, 7-Hydroxyaloin, ALOINOSIDE B.

Most Reported Compounds

Compound Sources Confidence
Flavonoids African journal of traditional, complementary, and alternative medicines : AJTCAM (and other 2 sources) ★☆☆☆☆
aloin Planta medica (and other 2 sources) ★☆☆☆☆
5-Hydroxyaloin A Planta medica (and other 1 sources) ★☆☆☆☆
7-Hydroxyaloin Talanta (and other 1 sources) ★☆☆☆☆
ALOINOSIDE B Planta medica (and other 1 sources) ★☆☆☆☆
Al African journal of traditional, complementary, and alternative medicines : AJTCAM (and other 1 sources) ★☆☆☆☆
Aloeresin A Planta medica (and other 1 sources) ★☆☆☆☆
Aloeresin C Planta medica (and other 1 sources) ★☆☆☆☆
Aloesin Planta medica (and other 1 sources) ★☆☆☆☆
Aloinoside A Planta medica (and other 1 sources) ★☆☆☆☆

Activities

Aloe ferox has 4 reported activities identified across 12 scientific publications and several other databases. The most consistently reported activities include Antioxidant, Antibacterial, Antifungal, Laxative.

Most Reported Activities

Activity Sources Confidence
Antioxidant Scientific reports (and other 2 sources) ★☆☆☆☆
Antibacterial Heliyon (and other 1 sources) ★☆☆☆☆
Antifungal Scientific reports (and other 1 sources) ★☆☆☆☆
Laxative Medicine (and other 1 sources) ★☆☆☆☆

Medicinal Uses

Aloe ferox has 19 reported medicinal uses identified across 12 scientific publications and several other databases. The most consistently reported uses include wound healing, Diabetes mellitus, anaplasmosis, babesiosis, backache.

Most Reported Uses

Use Sources Confidence
wound healing Journal of ethnopharmacology (and other 3 sources) ★★☆☆☆
Diabetes mellitus Natural product communications (and other 1 sources) ★☆☆☆☆
anaplasmosis Tropical animal health and production (and other 1 sources) ★☆☆☆☆
babesiosis Tropical animal health and production (and other 1 sources) ★☆☆☆☆
backache Frontiers in pharmacology (and other 1 sources) ★☆☆☆☆
blood pressure Medicine (and other 1 sources) ★☆☆☆☆
constipation Human & experimental toxicology (and other 1 sources) ★☆☆☆☆
ehrlichiosis Tropical animal health and production (and other 1 sources) ★☆☆☆☆
glycemic control Medicine (and other 1 sources) ★☆☆☆☆
headache Frontiers in pharmacology (and other 1 sources) ★☆☆☆☆

Preparations

Preparations Sources Confidence
ethanol extracts Journal of helminthology (and other 2 sources) ★☆☆☆☆
methanol Scientific reports (and other 2 sources) ★☆☆☆☆
A. ferox gel Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
A. ferox whole-leaf Journal of ethnopharmacology (and other 1 sources) ★☆☆☆☆
Cape Aloes Planta medica (and other 1 sources) ★☆☆☆☆
acetone Scientific reports (and other 1 sources) ★☆☆☆☆
acetone leaf Pakistan journal of pharmaceutical sciences (and other 1 sources) ★☆☆☆☆
acetone leaf extract Pakistan journal of pharmaceutical sciences (and other 1 sources) ★☆☆☆☆
acetone root extract Pakistan journal of pharmaceutical sciences (and other 1 sources) ★☆☆☆☆
aqueous leaf Pakistan journal of pharmaceutical sciences (and other 1 sources) ★☆☆☆☆