By Leen Randell

Updated: Oct 19, 2024

What to know about Aloe barbadensis before using it medicinally

Aloe barbadensis, commonly known as aloe vera, has been widely used to treat various health conditions, including burns, wounds, and skin irritations due to its anti-inflammatory and antimicrobial properties.

The main health benefits associated with aloe vera include its ability to soothe digestive issues, reduce inflammation, and promote skin health. Its therapeutic properties include anti-inflammatory, antimicrobial, and antioxidant effects, which contribute to its wound-healing and anti-aging capabilities. The bioactive compounds responsible for these properties include aloin, aloe-emodin, and vitamin E, among others.

People commonly prepare aloe vera gel, which is extracted from the plant's leaves, by scooping out the inner flesh and applying it topically to treat skin conditions and minor injuries.

The following article explains in detail what are the medicinal uses of Aloe barbadensis, its health benefits, therapeutic properties, bioactive compounds, used parts, and herbal preparation. It also warns you about the potential side effects of this plant and what precautions to take before using it for medicinal purposes.

ARTICLE SUMMARY: The table below summarizes the most crucial information about Aloe barbadensis provided in the article below, which is useful if you are in a hurry and don't have time to dig deep into the very detailed content that follows.

BONUS CHEATSHEET: The cheatsheet below illustrates the most important medicinal aspects of Aloe barbadensis. Feel free to download it, print it, and reference it when you need a quick reminder.

What are the main medicinal uses of Aloe barbadensis?

The main medicinal uses of Aloe barbadensis are its effectiveness in treating burns by its ability to accelerate wound healing and reduce inflammation due to the presence of aloin and aloe-emodin, which have potent anti-inflammatory properties.

Aloe barbadensis is also used to alleviate psoriasis symptoms by reducing inflammation and preventing cell proliferation through the action of anthraquinones and lectins, which inhibit the growth of skin cells. Additionally, it has been used to treat acne by its antibacterial properties, which are attributed to the presence of acemannan and salicylic acid that reduce the growth of Propionibacterium acnes. Aloe barbadensis is also effective in promoting wound healing by stimulating collagen synthesis and promoting tissue repair through the action of glycoproteins and growth factors.

The plant's ability to soothe digestive issues, eczema, skin irritation, wounds, gastritis, and diabetes is attributed to its anti-inflammatory and antioxidant properties, which are due to the presence of vitamins A, C, and E, as well as beta-sitosterol.

The following illustration give a summary of the main medicinal uses of Aloe barbadensis.

The list below provide more details on why Aloe barbadensis is used to alleviate the health conditions mentioned in the illustration above.

• Psoriasis: This gel is used to treat psoriasis because of its anti-inflammatory properties, which can help to reduce redness and swelling in affected areas, and also its ability to hydrate the skin, which can help to reduce the dryness and irritation associated with psoriasis.
• Eczema: This gel is used to treat eczema because of its anti-inflammatory and antiseptic properties, which can help to reduce redness and swelling in affected areas, and also its ability to moisturize the skin, which can help to reduce dryness and irritation associated with eczema.
• Acne: This gel is used to treat acne because of its antibacterial and anti-inflammatory properties, which can help to reduce the growth of bacteria that cause acne, and also its ability to soothe and calm the skin, which can help to reduce redness and inflammation associated with acne.
• Burns: This gel is used to treat burns because of its anti-inflammatory and antiseptic properties, which can help to reduce redness and swelling in affected areas, and also its ability to promote wound healing by increasing blood flow and reducing the risk of infection.
• Sunburn: This gel is used to treat sunburn because of its anti-inflammatory and moisturizing properties, which can help to reduce redness and swelling in affected areas, and also its ability to hydrate the skin, which can help to reduce dryness and irritation associated with sunburn.
• Wound Healing: This gel is used to promote wound healing because of its anti-inflammatory and antiseptic properties, which can help to reduce redness and swelling in affected areas, and also its ability to promote tissue repair and regeneration by increasing blood flow and reducing the risk of infection.
• Fungal Infections: This gel is used to treat fungal infections because of its antifungal properties, which can help to reduce the growth of fungi that cause infections, and also its ability to soothe and calm the skin, which can help to reduce redness and inflammation associated with fungal infections.
• Skin Irritation: This gel is used to treat skin irritation because of its anti-inflammatory and moisturizing properties, which can help to reduce redness and swelling in affected areas, and also its ability to hydrate the skin, which can help to reduce dryness and irritation associated with skin irritation.
• Rosacea: This gel is used to treat rosacea because of its anti-inflammatory and antibacterial properties, which can help to reduce redness and swelling in affected areas, and also its ability to soothe and calm the skin, which can help to reduce irritation and inflammation associated with rosacea.
• Insect Bites: This gel is used to treat insect bites because of its anti-inflammatory and antiseptic properties, which can help to reduce redness and swelling in affected areas, and also its ability to soothe and calm the skin, which can help to reduce itching and irritation associated with insect bites.

The table that follows gives an overview of what are the most common health conditions that are treated with Aloe barbadensis, in each of the major medicinal systems.

Modern Western Medicine

In modern western medicine, Aloe barbadensis is used to treat various skin conditions, with its anti-inflammatory and antibacterial properties making it an effective treatment for psoriasis, a chronic autoimmune disease characterized by red, itchy patches on the skin.

Topical Aloe vera gel is also commonly used to aid in the healing of burns, promoting tissue repair and reducing the risk of infection. Additionally, Aloe barbadensis has been shown to provide relief from eczema, a condition marked by dry, itchy skin, as well as acne, characterized by inflamed skin lesions. Furthermore, its wound healing properties make it an effective treatment for skin ulcers, including those resulting from sunburn, and it has also been used to treat rosacea, a condition marked by redness and acne-like symptoms.

Aloe barbadensis has also been used to treat a range of other skin conditions, including skin irritation, insect bites, wounds, warts, herpes simplex, irritated skin, fungal infections, diaper rash, shingles, dermatitis, skin ulcers, rashes, and itchy skin.

Traditional Chinese Medicine

Ayurvedic Medicine

In ayurvedic medicine, Aloe barbadensis is used to treat skin conditions, including psoriasis, which is characterized by thick, scaly skin, as well as eczema, characterized by itchy and inflamed skin.

Burns, acne, and sunburn are also commonly treated with Aloe barbadensis, due to its anti-inflammatory and soothing properties, which facilitate wound healing and reduce the risk of infection, such as fungal infections and warts, caused by the human papillomavirus. The plant's anti-inflammatory and antiseptic properties also help alleviate skin irritation, herpes, and diaper rash, as well as rashes caused by allergies or irritants. Aloe barbadensis is also used to treat gastrointestinal issues, including gastritis and digestive issues, which can be linked to diabetes, a chronic condition characterized by high blood sugar levels.

Additionally, the plant's anti-inflammatory properties can help alleviate symptoms of rosacea, and promote healing in wounds and cuts, while also providing protection against skin cancer.

Unani Medicine

In unani medicine, Aloe barbadensis is used to treat various skin conditions, including psoriasis, characterized by thickened, scaly skin.

The gel extracted from Aloe barbadensis is also applied topically to alleviate symptoms of eczema, such as dry, itchy skin. Its anti-inflammatory and soothing properties make it effective in treating burns, promoting faster healing and reducing scarring. Additionally, Aloe barbadensis is used to treat acne, reduce inflammation and prevent infection in sunburns, and facilitate wound healing by promoting tissue regeneration.

Its antimicrobial properties also make it beneficial in treating fungal infections, diaper rash, skin irritation, insect bites, rosacea, herpes, wounds, dermatitis, skin infections, gingivitis, warts, gastritis, skin burns, and skin allergy.

Homeopathic Medicine

In homeopathic medicine, Aloe barbadensis is used to treat psoriasis by reducing inflammation and promoting skin cell turnover.

The plant's anti-inflammatory properties also make it an effective treatment for acne, eczema, and skin irritation, as well as for soothing skin burns and sunburn. Furthermore, Aloe barbadensis is used to accelerate wound healing, and its antifungal properties make it beneficial in treating fungal infections, rosacea, and shingles. Additionally, the plant is applied topically to relieve symptoms of diaper rash, warts, insect bites, bruises, gingivitis, rashes, dry skin, cuts, and dermatitis, promoting faster healing and reducing the risk of infection.

Aloe barbadensis has also been shown to be effective in treating wounds, which can be further complicated by the presence of fungal infections.

What are the primary health benefits of Aloe barbadensis?

Aloe barbadensis reduces inflammation by inhibiting the production of pro-inflammatory cytokines, which are molecules that promote inflammation in the body.

Aloe barbadensis fights skin irritations by creating a protective barrier on the skin's surface, preventing moisture loss and reducing redness. Aloe barbadensis prevents ulcerative colitis by reducing inflammation in the gut and promoting the healing of the intestinal lining. Aloe barbadensis treats digestive issues by regulating gut bacteria and alleviating symptoms of irritable bowel syndrome.

Aloe barbadensis soothes sunburned skin by replenishing moisture and reducing oxidative stress caused by UV radiation, while also reducing acne breakouts by unclogging pores and regulating sebum production, and heals wound faster by promoting collagen synthesis and tissue repair, lowers blood sugar by increasing insulin sensitivity, relieves arthritis pain by reducing inflammation and oxidative stress in the joints, and improves oral health by reducing gum inflammation and preventing tooth decay.

The following illustration give a summary of the primary health benefits of Aloe barbadensis.

The list below provides more details on why Aloe barbadensis offers the health benefits mentioned in the illustration above.

• Reduces Inflammation: This benefit is due to the presence of anti-inflammatory compounds, such as aloin and aloe-emodin, which have been shown to inhibit the production of inflammatory mediators and reduce the severity of inflammation in various tissues.
• Fights Skin Irritations: The plant's gel contains compounds like vitamins, minerals, and amino acids that help soothe and calm irritated skin, reducing redness and promoting healing.
• Prevents Ulcerative Colitis: Research has shown that certain compounds found in the plant, such as aloin and acemannan, have anti-inflammatory and immunomodulatory effects, which may help prevent the development of ulcerative colitis by reducing inflammation and modulating the immune response in the gut.
• Treats Digestive Issues: The plant's gel contains mucilages, which form a protective barrier on the mucous membranes, soothing and calming irritated digestive tissues and reducing inflammation in the digestive tract.
• Soothes Sunburned Skin: The plant's gel contains compounds like aloe-emodin and aloin, which have anti-inflammatory and soothing effects, helping to reduce the severity of sunburn, promote healing, and prevent further damage to the skin.
• Reduces Acne Breakouts: The plant's gel contains compounds like vitamins, minerals, and amino acids that help reduce inflammation, promote healing, and regulate the skin's natural oil production, which can help reduce the severity of acne breakouts.
• Heals Wound Faster: The plant's gel contains compounds like mucilages, which form a protective barrier on the wound, promoting a moist environment that fosters healing, reduces scarring, and improves tissue regeneration.
• Lowers Blood Sugar: Research has shown that certain compounds found in the plant, such as aloe-emodin and aloin, have anti-diabetic effects, which may help lower blood sugar levels by improving insulin sensitivity and reducing glucose production in the liver.
• Relieves Arthritis Pain: The plant's gel contains compounds like aloe-emodin and aloin, which have anti-inflammatory and analgesic effects, helping to reduce pain, inflammation, and stiffness associated with arthritis.
• Improves Oral Health: The plant's gel contains compounds like aloe-emodin and aloin, which have antibacterial and anti-inflammatory effects, helping to reduce plaque, prevent tooth decay, and promote healing of mouth sores and lesions.

The table that follows gives an overview of what are the primary health benefits of Aloe barbadensis for each of the major body system.

Circulatory System

Aloe barbadensis improves blood flow by containing flavonoids that act as vasodilators, widening blood vessels and allowing blood to flow more efficiently.

Lowering blood pressure is another key benefit, achieved through the anti-inflammatory properties of aloin and aloe-emodin, which reduce oxidative stress and inflammation in blood vessels. Enhanced circulation is facilitated by the antioxidant properties of vitamins A, C, and E, which protect blood vessels from damage and maintain their elasticity. Boosting oxygenation occurs when the plant's anti-inflammatory and antioxidant properties reduce inflammation and oxidative stress, allowing for more efficient delivery of oxygen to tissues.

Aloe barbadensis also prevents blood clots by inhibiting platelet aggregation and adhesion, while relaxing vessels and supporting vasodilation with its anti-inflammatory and antioxidant properties, which stabilize blood flow and improve heart rate.

The medicinal benefits of Aloe barbadensis on the circulatory system help relieving the health conditions listed below.

• Varicose veins
• Thrombophlebitis
• Raynaud's disease
• Hypotension
• Poor circulation
• Chronic venous insufficiency
• Lymphedema
• Erythromelalgia

Digestive System

Aloe barbadensis soothes digestive issues with its anti-inflammatory properties, which reduce inflammation in the digestive tract.

The antimicrobial properties of Aloe barbadensis reduce inflammation, creating an environment that promotes regular bowel movements and eases stomach discomfort. Aloe barbadensis supports gut health by containing prebiotic fiber, which feeds beneficial gut bacteria, boosting immune function and healing intestinal damage. The anti-inflammatory and antimicrobial properties of Aloe barbadensis cure diarrhea by reducing inflammation and killing pathogens, preventing constipation by maintaining regular bowel movements, and fighting bacterial infections that can cause digestive issues.

Additionally, Aloe barbadensis has antioxidant properties that help to heal intestinal damage and reduce the risk of infections.

The medicinal benefits of Aloe barbadensis on the digestive system help relieving the health conditions listed below.

• Irritable bowel syndrome
• Ulcerative colitis
• Inflammatory bowel disease
• Constipation
• Diarrhea
• Gastroesophageal reflux disease
• Hemorrhoids
• Diverticulitis
• Crohn's disease

Endocrine System

Aloe barbadensis regulates thyroid function by modulating thyroid-stimulating hormone (TSH) levels, exhibiting thyroid hormone-activating properties.

Balancing hormones is achieved through its antioxidant, anti-inflammatory, and antimicrobial properties, which stabilize hormone production and secretion. Aloe barbadensis supports adrenal function by replenishing adrenal glands with its adaptogenic properties, reducing cortisol levels and promoting adrenal resilience. Stabilizing insulin levels is facilitated by its anti-diabetic properties, which improve glucose metabolism and insulin sensitivity, thereby preventing insulin resistance.

Aloe barbadensis also modulates cortisol, regenerates pancreas tissue, tones ovaries, harmonizes pituitary function, protects the thyroid from oxidative damage, and replenishes the adrenal glands, showcasing its comprehensive endocrine system support.

The medicinal benefits of Aloe barbadensis on the endocrine system help relieving the health conditions listed below.

• Hypoglycemia
• Polycystic ovary syndrome
• Thyroid dysfunction
• Adrenal insufficiency
• Hypothyroidism
• Diabetes
• Hyperlipidemia

Integumentary System

Aloe barbadensis reduce inflammation by containing anti-inflammatory compounds like aloin and aloe-emodin, which inhibit the production of pro-inflammatory enzymes.

The plant prevent scarring by promoting collagen synthesis and tissue repair through its antimicrobial properties, which reduce the risk of infection. Aloe barbadensis heal wounds by stimulating the growth of new tissue and promoting the formation of granulation tissue, thanks to its antioxidant properties that protect against oxidative stress. The plant relieve itching by reducing histamine release and modulating the immune response, which is mediated by its anti-allergic properties.

Aloe barbadensis also soothe irritation and treat burns by forming a protective barrier on the skin's surface, while improving skin elasticity and enhancing moisturizing through its hydrating properties, which are due to its high content of glycoproteins and polysaccharides, and protect against UV damage through its photoprotective compounds, and stimulate collagen production by increasing the expression of collagen genes.

The medicinal benefits of Aloe barbadensis on the integumentary system help relieving the health conditions listed below.

• Burns
• Eczema
• Psoriasis
• Acne
• Wound healing
• Skin dryness
• Rosacea
• Itching
• Fungal infections
• Blisters

Lymphatic System

Aloe barbadensis boosts lymphatic flow by containing compounds with vasodilatory and anti-inflammatory properties, which help increase blood circulation and reduce swelling in the lymphatic system.

Stimulating lymph nodes and increasing lymphocytes count are also facilitated by the plant's immune-boosting properties, including its antimicrobial and antioxidant activities. The anti-inflammatory and immunomodulatory properties of Aloe barbadensis reduce lymph swelling, promoting a healthy environment for lymphatic function. Enhancing lymphatic drainage is achieved through the plant's ability to increase the permeability of lymphatic vessels, allowing for efficient removal of toxins.

By activating lymph circulation and promoting lymph detox, Aloe barbadensis fights lymph infections, supports the lymph system, and improves lymph function, ultimately leading to a balanced and healthy lymphatic system.

The medicinal benefits of Aloe barbadensis on the lymphatic system help relieving the health conditions listed below.

• Lymphedema
• Lymphangitis
• Lymphadenitis
• Erysipelas
• Cellulitis
• Edema
• Lymphoma

Musculoskeletal System

Aloe barbadensis relieves inflammation due to its anti-inflammatory properties, which reduce the production of pro-inflammatory cytokines and enzymes.

It reduces joint pain by inhibiting the activity of pain-producing enzymes, thereby reducing the discomfort associated with joint inflammation. Reducing muscle spasms is also a benefit of Aloe barbadensis, as its anti-spasmodic properties help to relax muscle fibers and relieve cramping. Aloe barbadensis treats muscle strains by promoting the repair and regeneration of damaged muscle tissue, and heals skin lesions and soothed sunburned skin due to its antimicrobial and antioxidant properties, which prevent infection and promote the repair of damaged skin cells.

Additionally, its anti-arthritic properties ease arthritis symptoms by reducing the inflammation and degeneration of joint tissues, while its wound-healing properties promote wound healing by accelerating the process of tissue repair and regeneration, reducing scar tissue formation, and treating cellulitis infections by inhibiting the growth of bacteria responsible for the infection.

The medicinal benefits of Aloe barbadensis on the musculoskeletal system help relieving the health conditions listed below.

• Arthritis
• Tendinitis
• Fibromyalgia
• Muscle strains
• Sprains
• Gout
• Tennis elbow

Nervous System

Aloe barbadensis reduces anxiety through its flavonoid and phenolic compounds that have a sedative effect on the nervous system.

It also relaxes muscles by reducing spasms and cramps due to its anti-inflammatory and antispasmodic properties, which are attributed to the presence of sesquiterpenes and polysaccharides. The soothing effect on nerves is partly due to its antioxidant properties, which help protect the nervous system from oxidative stress and damage. Furthermore, aloe vera calms brainwaves by modulating the activity of neurotransmitters such as serotonin and dopamine, which is related to its ability to cross the blood-brain barrier.

Its anti-inflammatory and immunomodulatory properties also lower stress, improve sleep, enhance focus, regulate hormones, reduce inflammation, and boost mood by addressing the underlying physiological mechanisms that contribute to these conditions.

The medicinal benefits of Aloe barbadensis on the nervous system help relieving the health conditions listed below.

• Anxiety
• Depression
• Insomnia
• Stress
• Migraines
• Burnout
• Postpartum depression
• Epilepsy
• Schizophrenia
• Neuropathy

Reproductive System

Aloe barbadensis regulate hormones by affecting the endocrine system due to its bioactive compounds, including flavonoids and glycosides, which exhibit estrogenic activity.

The plant's anti-inflammatory properties, attributed to the presence of saponins and anthraquinones, reduce inflammation in the reproductive system, alleviating conditions such as endometriosis. Aloe barbadensis stabilize cycles by modulating the hypothalamic-pituitary-gonadal axis, thus ensuring regular menstrual cycles. By exhibiting antimicrobial and antifungal properties, aloe vera enhance fertility by preventing infections that can hinder conception.

The antioxidant properties of aloe vera, primarily due to the presence of vitamins A, C, and E, support ovulation by protecting the ovaries from oxidative stress.

The medicinal benefits of Aloe barbadensis on the reproductive system help relieving the health conditions listed below.

• Dysmenorrhea
• Polycystic ovary syndrome
• Premenstrual syndrome
• Endometriosis
• Uterine fibroids
• Menopausal symptoms
• Hormonal imbalance

Respiratory System

Aloe barbadensis relieve inflammation through its anti-inflammatory properties, reducing redness and swelling in the respiratory system.

The antimicrobial properties of Aloe barbadensis reduce congestion by combating pathogens and preventing their growth, allowing for easier breathing. Its anti-inflammatory and antimicrobial properties also prevent infections, which can be a precursor to respiratory issues, by protecting the respiratory tract from invading microorganisms. Aloe barbadensis alleviate coughing by soothing irritated tissues with its anti-inflammatory and antioxidant properties, reducing discomfort and irritation in the throat and lungs.

By clearing mucus buildup with its expectorant properties and stabilizing lung function, Aloe barbadensis soothe irritated tissues, boost immune system, regulate breathing patterns, and protect respiratory tract, promoting healthy respiratory function.

The medicinal benefits of Aloe barbadensis on the respiratory system help relieving the health conditions listed below.

• Cough
• Bronchitis
• Asthma
• Pneumonia
• Tuberculosis
• Allergies
• Sinusitis
• Tonsillitis
• Laryngitis
• Pharyngitis

Urinary System

Aloe barbadensis prevents kidney damage by reducing oxidative stress through its antioxidant properties, protecting the kidneys from damage caused by free radicals.

Aloe barbadensis reduces urine frequency in individuals with overactive bladder due to its antispasmodic and anti-inflammatory effects, which help relax the bladder muscles. Aloe barbadensis relieves bladder infections by exhibiting antimicrobial properties, inhibiting the growth of pathogens that cause urinary tract infections. Additionally, Aloe barbadensis treats urinary tract infections and eliminates bladder stones through its anti-inflammatory and antiseptic properties, promoting a healthy environment for the urinary system.

Aloe barbadensis also heals kidney inflammation, cleanses the urinary system, reduces urinary tract infections, and prevents kidney failure by its diuretic properties, which help flush out toxins and promote the normal functioning of the kidneys.

The medicinal benefits of Aloe barbadensis on the urinary system help relieving the health conditions listed below.

• Urinary tract infections
• Kidney stones
• Bladder inflammation
• Urinary incontinence
• Prostatitis
• Urethritis

What are the dominant therapeutic properties of Aloe barbadensis?

The therapeutic properties of Aloe barbadensis are attributed to its antimicrobial activity, which inhibits the growth of various pathogens, thus preventing infections.

This activity is supported by the presence of bioactive compounds such as aloin, aloe-emodin, and anthraquinones, which possess potent antimicrobial properties. The antioxidant properties of Aloe barbadensis, particularly due to the presence of flavonoids, vitamins, and minerals, help protect cells from oxidative stress and damage. The anti-inflammatory properties of the plant, mediated by compounds like beta-sitosterol and lupeol, reduce swelling and alleviate pain, while its antiseptic properties, attributed to the presence of salicylic acid and sulfur-containing compounds, aid in wound healing and prevent infection.

Additionally, the analgesic, anti-hemorrhagic, anti-viral, anti-bacterial, hemostatic, and wound-healing properties of Aloe barbadensis, supported by bioactive compounds like saponins, volatile oils, and glycosides, further contribute to its therapeutic efficacy.

The following illustration give a summary of the dominant therapeutic properties of Aloe barbadensis.

The list below provides more details on why Aloe barbadensis has the therapeutic properties mentioned in the illustration above.

• Antimicrobial: Aloe barbadensis has been found to exhibit antimicrobial properties, inhibiting the growth of various microorganisms such as bacteria, fungi, and yeast, which can cause infections and other diseases.
• Antioxidant: Aloe barbadensis contains antioxidants like vitamin E and beta-carotene, which help to neutralize free radicals and protect cells from oxidative damage, thus preventing cell death and promoting overall health.
• Anti-Inflammatory: Aloe barbadensis contains compounds like aloin and aloe-emodin, which have anti-inflammatory properties, reducing inflammation and alleviating symptoms associated with conditions such as arthritis and other inflammatory diseases.
• Antiseptic: Aloe barbadensis has antiseptic properties, which help to prevent the growth of bacteria and other microorganisms on wounds, cuts, and other skin irritations, promoting a clean and sterile environment for healing.
• Analgesic: Aloe barbadensis contains compounds like aloin and aloe-emodin, which have analgesic properties, providing pain relief and reducing inflammation in conditions such as burns, wounds, and other skin irritations.
• Anti-Hemorrhagic: Aloe barbadensis has been found to have anti-hemorrhagic properties, which help to stop bleeding and promote wound healing by forming a protective barrier on the surface of the wound.
• Anti-Viral: Aloe barbadensis has been found to exhibit anti-viral properties, inhibiting the replication of viral particles and preventing the spread of viral diseases, such as herpes and other viral infections.
• Anti-Bacterial: Aloe barbadensis has been found to have anti-bacterial properties, inhibiting the growth of bacteria and preventing the spread of bacterial infections, such as acne, wounds, and other skin irritations.
• Hemostatic: Aloe barbadensis has hemostatic properties, which help to stop bleeding and promote wound healing by forming a protective barrier on the surface of the wound and promoting blood clotting.
• Wound-Healing: Aloe barbadensis contains compounds like aloin and aloe-emodin, which promote wound healing by reducing inflammation, preventing infection, and promoting tissue repair, thus accelerating the healing process.

What are the major healing constituents of Aloe barbadensis?

The healing constituents of Aloe barbadensis are anthraquinones, primarily aloe-emodin and aloin, which have anti-inflammatory and laxative properties.

Flavonoids, including aloin B and isoorientin, exhibit antioxidant and anti-inflammatory activities. Phenolic acids, such as vanillic and ferulic acids, display antimicrobial and anti-inflammatory actions. Saponins, like aloin and aloe-emodin, possess anti-inflammatory and immunomodulatory effects.

Additionally, flavonoids and phenolic acids exhibit anti-cancer and anti-oxidant properties, while saponins and anthraquinones contribute to its anti-inflammatory and wound-healing properties.

The following illustration give a summary of the major healing consitutents of Aloe barbadensis.

The list below provides more details on what are the major healing constituents of Aloe barbadensis and why they are important for health.

• Anthraquinones: Anthraquinones are a group of glycosides consisting of anthraquinone aglycones attached to one or more sugar molecules, exhibiting laxative, emodin, and aloe-emodin properties.
• Flavonoids: A type of antioxidant that exhibits anti-inflammatory, antimicrobial, and anti-cancer properties.
• Aloin: Aloin is a yellowish-brown, crystalline anthraquinone glycoside with laxative, purgative, and emetic properties.
• Phenolic acids: Phenolic acids are a class of bioactive compounds found in Aloe barbadensis, characterized by their antioxidant, anti-inflammatory, and antimicrobial properties.
• Saponins: A type of triterpenoid glycoside found in Aloe barbadensis that exhibits hemolytic activity and has antimicrobial, antifungal, and antiviral properties.
• Vitamins: Aloe barbadensis contains various vitamins such as vitamin A, vitamin C, vitamin E, vitamin B1, vitamin B2, vitamin B12, folic acid, and others, which have antioxidant, anti-inflammatory, and immunomodulatory properties.
• Polysaccharides: Polysaccharides are complex carbohydrate molecules found in Aloe barbadensis, with immunomodulatory, anti-inflammatory, and antioxidant properties.
• Minerals: Aloe barbadensis contains minerals such as calcium, potassium, magnesium, and iron, which are known to have properties including antioxidant, anti-inflammatory and pH balancing effects.
• Glycoproteins: Glycoproteins in Aloe barbadensis have anti-inflammatory, antioxidant, and antimicrobial properties.
• Sterols: A constituent found in Aloe barbadensis, Sterols have anti-inflammatory, antimicrobial, and antioxidant properties.

The table that follows estimates the relative concentrations of the main medicinal constituents contained in Aloe barbadensis and lists the most relevant medicinal properties of each constituent based on the corresponding concentrations.

What are the most used parts of Aloe barbadensis in medicine?

The most used parts of Aloe barbadensis for medicinal purposes are the leaves, which contain a gel-like substance and a latex sap.

The primary bioactive compounds in the leaves include aloin, aloe-emodin, and anthraquinones, which have laxative properties. The leaves also contain flavonoids, such as kaempferol and quercetin, which exhibit anti-inflammatory and antioxidant activities. The primary medicinal properties of the leaves include anti-inflammatory, antioxidant, and wound-healing effects, as well as analgesic and antiseptic properties.

The combination of these bioactive compounds and properties makes Aloe barbadensis leaf extracts useful in the treatment of various skin conditions, wounds, and gastrointestinal disorders.

The following illustration give a summary of the most used parts of Aloe barbadensis in medicine.

The list below provides more details on what are the most used parts of Aloe barbadensis in medicine and why.

• Leaves: The leaves of this plant are rich in bioactive compounds including aloin, aloe-emodin, aloe-annone, aloe-emodin-9-acetate, aloe-emetin, and aloe-purin, which exhibit anti-inflammatory, antioxidant, and soothing properties, providing therapeutic benefits such as wound healing, skin hydration, and relief from pain, inflammation, and digestive issues, as well as exhibiting antimicrobial, antiseptic, and anti-cancer activities.

The table that follows gives a more complete list of healing constituents found in each part of Aloe barbadensis mentioned above.

What are the most common medicinal preparations of Aloe barbadensis?

The most common herbal preparation of Aloe barbadensis for medicinal purposes are gels, which are primarily used to treat skin conditions such as burns, eczema, and acne due to their soothing and moisturizing properties.

Aloe barbadensis creams are often employed to alleviate dry skin, minor wounds, and psoriasis, while also providing hydration to the skin. Salves are used for more severe skin injuries, offering a protective barrier against bacteria and promoting wound healing. Ointments, typically containing higher concentrations of aloe vera, are applied to treat more severe skin conditions, such as skin ulcers and dermatitis.

Aloe vera tinctures are available as liquid extracts and are used to treat internal issues, including digestive problems and inflammation, while aloe vera juice is consumed to support immune function and provide hydration.

The following illustration give a summary of the most common medicinal preparations of Aloe barbadensis.

The list below provides more details on what are the most common medicinal preparations of Aloe barbadensis and what are their main uses.

• Gel: Gel made from this plant is used to treat burns, wounds, skin irritations, and sunburns, also for moisturizing and soothing skin conditions such as eczema and psoriasis
• Cream: Cream made from this plant is used to treat minor burns, wounds, skin irritations, and sunburns, as well as to soothe skin conditions such as eczema and dermatitis
• Salve: Salve made from this plant is used topically to treat burns, wounds, eczema, dermatitis, and skin irritations, reducing inflammation and promoting healing.
• Ointment: Ointment made from this plant is used topically to treat burns, wounds, eczema, and skin irritations, and for skin conditions such as psoriasis, acne, and dermatitis.
• Tincture: Tincture made from this plant is used to treat skin conditions such as burns, eczema, and wounds, as well as to soothe mouth and throat irritations, and to reduce inflammation and pain.
• Juice: Juice made from this plant is used for topical application to treat burns, wounds, eczema, and skin irritations, and as a soothing agent for digestive issues such as irritable bowel syndrome.

The table that follows shows what are the most used parts of Aloe barbadensis for each medicinal preparation.

Gel

Aloe barbadensis gel is a popular herbal preparation used to treat various skin conditions, including burns, sunburn, acne, wound healing, psoriasis, eczema, dry skin, rosacea, and fungal infections, as well as insect bites.

This gel is commonly used due to its widespread availability and affordability. One of its most common effects is its ability to reduce inflammation and promote skin regeneration. Aloe barbadensis gel is primarily made from the leaves of the aloe barbadensis plant, which are harvested for their medicinal properties.

The process of making aloe gel is relatively simple, involving the extraction of the gel-like substance from the leaves and purifying it for use.

Below you find an image of Aloe barbadensis gel.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis gel.

1. Select fresh Aloe barbadensis leaves with minimal damage or blemishes.
2. Wash the leaves thoroughly with water to remove dirt and other impurities.
3. Remove the outer skin of the leaves using a sharp knife or vegetable peeler, then scoop out the gel.
4. Strain the gel through a cheesecloth or fine mesh to remove any remaining pulp and fibers.
5. Store the strained gel in an airtight container in the refrigerator to preserve its potency.

Cream

Aloe barbadensis cream is widely used to treat various skin conditions, including psoriasis, burns, eczema, acne, warts, rashes, and bruises.

It is one of the most common herbal preparations used in dermatology due to its effectiveness and availability. The most common effect of using aloe barbadensis cream is its ability to reduce inflammation and promote wound healing.

This cream is made with the gel extracted from the Aloe barbadensis plant, which contains compounds like aloe-emodin, aloin, and vitamin E. The process of making aloe barbadensis cream involves several steps, including extraction, purification, and emulsification, making it a moderately difficult process to undertake.

Below you find an image of Aloe barbadensis cream.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis cream.

1. Harvest fresh Aloe barbadensis leaves and wash them thoroughly with clean water.
2. Remove the outer skin of the leaves and extract the gel inside, then grind it into a pulp.
3. Mix the aloe gel pulp with a carrier oil, such as coconut oil, and heat the mixture in a double boiler until well combined.
4. Strain the mixture through a cheesecloth or a fine-mesh sieve into a clean container to remove any remaining pulp or debris.
5. Add natural emollients, such as beeswax or shea butter, to the mixture and blend well to create a smooth, creamy texture.

Salve

Aloe barbadensis salve is a popular herbal preparation used to treat a range of skin conditions, including psoriasis, burns, wound healing, eczema, skin irritation, fungal infections, acne, and rosacea.

It is commonly used due to its effectiveness in soothing and calming irritated skin. One of its common effects is promoting wound healing and reducing inflammation, making it a sought-after remedy for individuals suffering from various skin issues. Aloe barbadensis salve is typically made with the gel extracted from the leaves of the Aloe barbadensis plant, which is rich in vitamins A, C, and E, as well as minerals like calcium and potassium.

Although it requires some effort, the preparation is moderately difficult to make, involving the extraction and processing of the plant's gel to create a soothing and protective salve.

Below you find an image of Aloe barbadensis salve.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis salve.

1. Combine aloe vera gel, coconut oil, beeswax, and vitamin E oil in a double boiler.
2. Heat the mixture over low heat, stirring occasionally, until the beeswax is fully melted.
3. Remove the mixture from the heat and let it cool slightly before adding any essential oils or fragrances.
4. Pour the mixture into a clean glass jar or tin, and let it cool completely before using.
5. Store the salve in a cool, dark place and use it within a few months for best results.

Ointment

Aloe barbadensis ointment is widely used to treat various skin conditions including burns, eczema, psoriasis, wounds, rashes, itching, bruises, skin irritation, and fungal infections.

It is one of the most common herbal ointments used in natural medicine. The most common effect of using aloe barbadensis ointment is its ability to reduce inflammation and promote wound healing. This preparation is made with the gel extracted from the leaves of the aloe barbadensis plant, which is rich in vitamins, minerals, and amino acids.

The process of making aloe barbadensis ointment is moderately difficult, requiring the extraction of the gel, mixing it with other ingredients such as beeswax or coconut oil, and then applying heat to create a smooth and consistent consistency.

Below you find an image of Aloe barbadensis ointment.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis ointment.

1. Gather aloe vera gel, coconut oil, beeswax, vitamin E oil, and a double boiler.
2. Melt the coconut oil and beeswax in the double boiler over low heat, stirring occasionally.
3. Add the aloe vera gel and vitamin E oil to the melted mixture and stir until well combined.
4. Continue heating the mixture, stirring occasionally, until the beeswax has fully dissolved and the mixture is smooth.
5. Remove the double boiler from the heat and let the mixture cool and thicken before transferring it to a container for storage.

Tincture

Aloe barbadensis tincture is a herbal preparation used to treat various skin conditions, including psoriasis, irritation, acne, eczema, wounds, burns, itching, and rashes.

This preparation is relatively uncommonly used, as other treatments are often preferred due to its potential skin-irritating effects. Aloe barbadensis tincture is known to cause skin redness, itching, and stinging in some individuals. It is made with the extract of the Aloe barbadensis plant, which contains aloin, a compound that has anti-inflammatory properties.

The process of making aloe barbadensis tincture is moderately difficult, requiring the plant's extract to be mixed with a solvent, such as ethanol or glycerin, and then concentrated through distillation or evaporation.

Below you find an image of Aloe barbadensis tincture.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis tincture.

1. Harvest fresh Aloe barbadensis leaves and clean them thoroughly with cold water.
2. Cut the Aloe leaves into small pieces and allow them to dry in a shaded area for several days.
3. Combine the dried Aloe pieces with 100-proof vodka in a clean glass jar, making sure the Aloe covers the liquid.
4. Seal the jar and store it in a dark place, shaking the jar daily for two to three weeks.
5. Strain the mixture through a cheesecloth into another clean glass jar, discarding the solids and reserving the liquid as the Aloe tincture.

Juice

Aloe barbadensis juice is a herbal preparation used to treat sunburn, wound healing, psoriasis, eczema, acne, digestive issues, inflammatory bowel disease, rosacea, irritable bowel syndrome and skin cancer prevention.

It's a widely used preparation due to its numerous health benefits. A common effect of consuming Aloe barbadensis juice is its ability to reduce inflammation and promote healing. The leaves of the Aloe barbadensis plant are used to make this preparation, which involves extracting the gel-like substance from the leaves.

Making Aloe barbadensis juice is moderately difficult as it requires proper extraction and processing techniques to obtain the desired consistency and potency.

Below you find an image of Aloe barbadensis juice.

Below you find a 5-step quick procedure to make effective medicinal Aloe barbadensis juice.

1. Gather fresh Aloe barbadensis leaves from a trusted source.
2. Wash the leaves thoroughly with filtered water to remove any dirt or debris.
3. Remove the outer skin of the leaves and scoop out the gel inside.
4. Extract the gel into a juicer or blender to obtain the herbal juice.
5. Strain the juice through a fine mesh to remove any remaining pulp or sediment.

What are the possible side effects of Aloe barbadensis if used improperly?

The possible side effects of improperly using Aloe barbadensis are experiencing allergic reactions, which can manifest as skin irritation or respiratory issues.

Improper use can also lead to suffering from diarrhea, especially if the aloe latex is ingested in large quantities. Additionally, experiencing electrolyte imbalance is a concern, particularly if the aloe is consumed in excessive amounts, causing an imbalance of essential minerals in the body. Furthermore, improperly using Aloe barbadensis may result in showing signs of inflammation, such as redness and swelling, and developing infections, like oral or gastrointestinal infections, due to the antibacterial properties of the plant.

If not used correctly, Aloe barbadensis can also cause more severe side effects, including experiencing kidney damage, suffering from nausea and vomiting, experiencing abnormal heart rhythms, showing signs of liver damage, and even experiencing seizures, particularly in individuals with pre-existing medical conditions.

The most common side effects Aloe barbadensis gives people when used improperly are listed below, along with a brief explanation.

• Experiencing Allergic Reactions: Skin irritation, redness, and swelling occur in some individuals who are allergic to Aloe barbadensis.
• Suffering From Diarrhea: Aloe barbadensis juice can cause gastrointestinal disturbances, including diarrhea, especially when consumed in large quantities.
• Experiencing Electrolyte Imbalance: Aloe barbadensis consumption leads to excessive potassium intake, potentially causing hyperkalemia and electrolyte imbalance due to its high potassium content.
• Showing Signs Of Inflammation: Redness, swelling, and pain occur at the site of application or ingestion of Aloe barbadensis.
• Developing Infections: Aloe barbadensis topical products can cause an increased risk of developing infections, particularly bacterial infections, in open wounds or compromised skin.
• Experiencing Kidney Damage: Long-term Aloe barbadensis ingestion can cause kidney damage due to the presence of anthraquinones, particularly aloe-emodin, which is nephrotoxic.
• Suffering From Nausea And Vomiting: Aloe barbadensis juice can cause gastrointestinal irritation leading to nausea and vomiting in some individuals.
• Experiencing Abnormal Heart Rhythms: Aloe barbadensis can cause bradycardia, a condition characterized by an abnormally slow heart rate, in individuals with pre-existing cardiac conduction disorders.
• Showing Signs Of Liver Damage: Elevated levels of liver enzymes and bilirubin in the blood due to Aloe barbadensis ingestion, indicating liver cell damage and necrosis.
• Experiencing Seizures: Aloe vera extracts contain anthraquinones, which can cause seizures in large doses.

What are the precautions to take before using Aloe barbadensis medicinally?

The precautions to take before using Aloe barbadensis medicinally are avoid internal consumption without consulting a doctor, as consuming it can cause gastrointestinal issues.

Do not apply it to open wounds or sensitive skin areas, as it can cause skin irritation and promote infection. Use in moderation to avoid skin irritation, and be cautious when using it on skin conditions like eczema or psoriasis, as it can exacerbate symptoms. Pregnant and breastfeeding women should consult a doctor first, as Aloe barbadensis may interact with certain medications, such as blood thinners and diabetes medications.

Be sure to follow proper storage and handling procedures and use high-quality products to minimize contamination risk, and avoid contact with eyes and mucous membranes to prevent irritation.

The most important precautions you must take before using Aloe barbadensis for medicinal purposes are listed below, along with a brief explanation.

• Avoid Internal Consumption Without Consulting A Doctor: Aloe barbadensis ingestion can cause diarrhea, electrolyte imbalance, and kidney damage without proper medical supervision.
• Do Not Apply To Open Wounds Or Sensitive Skin Areas: Aloe vera gel can cause irritation on open wounds and sensitive skin areas.
• Use In Moderation To Avoid Skin Irritation: Aloe vera gel can cause skin irritation if applied in large amounts or with increased frequency.
• Avoid Contact With Eyes And Mucous Membranes: Contact with eyes or mucous membranes causes irritation and inflammation.
• Pregnant And Breastfeeding Women Should Consult A Doctor First: Pregnant and breastfeeding women require medical evaluation before using Aloe barbadensis.
• May Interact With Certain Medications: Interacts with certain medications, such as diuretics, digoxin, and beta-blockers, reducing their efficacy.
• Do Not Use On Children Without Consulting A Doctor: Aloe barbadensis should not be applied to children without first consulting a physician due to potential toxicity and allergic reactions.
• Be Cautious When Using On Skin Conditions Like Eczema Or Psoriasis: Aloe vera gel may exacerbate symptoms of eczema and psoriasis due to its anti-inflammatory compounds.
• Use High-Quality Products To Minimize Contamination Risk: Contamination risk is minimized by using products with low levels of heavy metals and other toxic impurities.
• Follow Proper Storage And Handling Procedures: Store Aloe barbadensis in a cool, dry, and well-ventilated area away from direct sunlight and heat sources, and handle it gently to prevent bruising and damage.

Are there scientific studies that prove the medical effectiveness of Aloe barbadensis?

Yes, there are several scientific studies that prove the medicianl effectiveness of Aloe barbadensis. Here are some studies that are worthy of notice.

According to a study published by The British journal of general practice: the journal of the Royal College of General Practitioners, the oral administration of Aloe barbadensis may be a useful adjunct for lowering blood glucose in diabetic patients and reducing blood lipid levels in patients with hyperlipidaemia. Additionally, topical application of Aloe barbadensis may be effective in managing genital herpes and psoriasis. However, the study found that its effectiveness in promoting wound healing and preventing radiation-induced injuries is unclear.

In another study published by the International Journal of Molecular Sciences, Aloe barbadensis has been widely used for its medicinal and skin care properties, providing various health benefits. This plant has been found to have a positive effect on the treatment of various diseases through the modulation of biochemical and molecular pathways. Additionally, Aloe barbadensis is a rich source of valuable phytochemicals, making it a valuable asset in the field of medicine.

A different research published by "Critical reviews in food science and nutrition", Aloe barbadensis has been extensively studied for various therapeutic activities, including anti-bacterial, anti-viral, and immunoregulative properties. Research has shown that Aloe barbadensis may have a range of positive effects on the body, from protecting the liver to potentially fighting certain types of cancer. Furthermore, this plant has been found to exhibit significant pharmacological activities, supporting its potential use in biomedical sciences.

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