Alangium vitiense
Alangium vitiense · Accepted scientific name
Scientific literature: Very Sparse (2 studies) · ★☆☆☆☆
Alangium vitiense is a botanical species currently being investigated for its significant pharmacological potential. Recent research has focused on its oncostatic activities, specifically targeting various cancer cell lines. Experimental studies have demonstrated its effectiveness against L1210 and P388 leukemia conditions. These biological effects were observed through the application of total alkaloid preparations as well as purified alkaloid extracts. Further analysis involved testing two specific purified alkaloid extracts to isolate their precise therapeutic mechanisms.
- Synonyms
- Stylidium Vitiense · Alangium Villosum Subsp. Vitiense · 6 more
- Common names
- Not available
- Family
- Cornaceae
- Distribution
- Africa
- Plant Parts
- Not available
Classification
Synonyms
Alangium vitiense is a botanical species characterized by a complex history of taxonomic synonyms. Scientific literature identifies this plant under various names, including the previously recognized Marlea bussyana and Karangolum vitiense. It is also closely linked to the nomenclature of Alangium bussyanum in several botanical records. Furthermore, the species has been categorized under different subspecies, such as Alangium villosum subsp. bussyanum and Alangium villosum subsp. vitiense. Understanding these shifting classifications is essential for accurately identifying the plant within its diverse evolutionary lineage.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Alangium vitiense is a unique botanical specimen that belongs to the kingdom Plantae. Within this vast biological realm, the plant is classified under the class Equisetopsida. It is further organized into the order Cornales, which helps scientists understand its evolutionary lineage. As a member of the family Cornaceae, it shares distinct characteristics with its close relatives. Ultimately, this species is defined by its placement within the genus Alangium.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Cornales |
| Family | Cornaceae |
| Genus | Alangium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Alangium vitiense is a notable plant species primarily found throughout the vast expanse of the Pacific region. Its natural range is concentrated within the Southwestern Pacific, where it plays a role in local ecosystems. Specifically, this species can be identified growing across the islands of Fiji and Vanuatu. Additionally, its distribution extends to the lush landscapes of New Caledonia. These geographical connections highlight the plant's significance within this specific oceanic territory.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Alangium vitiense grows in a robust tree form, establishing a sturdy presence within its ecosystem. As a self-supporting species, it maintains its own structure without the need for external assistance.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Alangium vitiense has demonstrated significant oncostatic activity against several specific types of murine lymphoid neoplasms. Research indicates that both total alkaloid and purified alkaloid extracts from the plant effectively target L1210 leukemia in mice. Furthermore, these extracts have shown noticeable effectiveness against P388 leukemia and Gardner lymphosarcoma. However, the therapeutic impact appears to be selective, as no activity was observed against B16 melanoma or WEHI3 myelomonocytic leukemia. This specific potency suggests that the plant's alkaloids hold specialized potential for treating certain lymphoid malignancies.
Compounds
Conditions
Alangium vitiense demonstrates significant oncostatic activity against various murine lymphoid neoplasms. Specifically, extracts from this plant are effective in treating L1210 leukemia. The plant also shows therapeutic potential against Gardner lymphosarcoma. Furthermore, Alangium vitiense is capable of treating P388 leukemia. These findings confirm its ability to target two other lymphoid neoplasias in mice.
Preparations
Alangium vitiense is prepared as a total alkaloid to test its oncostatic effects on murine lymphoid neoplasms. This plant is also prepared as purified alkaloid extracts for experimental screening against specific leukemia types. Furthermore, Alangium vitiense is prepared as two purified alkaloid extracts which demonstrate varying levels of activity. These different preparations are evaluated for their ability to combat L1210 leukemia and other lymphoid neoplasias in mice. Through these specific preparations, researchers can distinguish between the noticeable activity of the total alkaloid and the borderline activity of the purified extracts.