Alangium javanicum
Alangium javanicum · Accepted scientific name
Scientific literature: Very Sparse (0 studies) · ★☆☆☆☆
Alangium javanicum is a significant medicinal plant species widely distributed across various tropical regions. In recent pharmacological studies, researchers have focused on investigating its complex chemical profile to uncover potential therapeutic benefits. This investigation specifically utilizes crude CH2Cl2-MeOH extracts to isolate and analyze its bioactive constituents. These methanol and dichloromethane solvent combinations are essential for capturing a broad spectrum of secondary metabolites. Through this targeted preparation, the plant's medicinal properties can be more effectively evaluated for future pharmaceutical applications.
- Synonyms
- Marlea Javanica · Marlea Costata · 4 more
- Common names
- Not available
- Family
- Cornaceae
- Distribution
- Australasia
- Plant Parts
- Not available
Classification
Common Names
Alangium javanicum is a botanical species known by several distinct regional names. In certain areas, this plant is affectionately referred to by its common name, Lajik. It is also frequently identified by the name Ridan among local communities. These varying monikers highlight the diverse linguistic landscape surrounding the species. Understanding these different names is essential for accurate identification in different geographical contexts.
Sources: Catalogue of Life (COL)
Synonyms
Alangium javanicum is a botanical species characterized by a complex history of taxonomic classifications. Throughout various studies, it has been identified by several synonyms, including the names Alangium arboreum and Alangium bogoriense. Researchers have also documented its relationship to Alangium costatum within the same family. Furthermore, the plant has previously been cataloged under the genus Marlea as both Marlea costata and Marlea javanica. Understanding these overlapping names is essential for maintaining accurate botanical records and ensuring scientific clarity.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Alangium javanicum is a distinctive species that belongs to the vast kingdom Plantae. Within this botanical realm, it is classified under the class Equisetopsida. Its taxonomic journey continues through the order Cornales, which helps define its evolutionary lineage. The plant is further nested within the family Cornaceae, showcasing its structural similarities to related species. Ultimately, it is identified by its specific genus, Alangium, marking its unique place in the natural world.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Cornales |
| Family | Cornaceae |
| Genus | Alangium |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Alangium javanicum is a plant species primarily found within the diverse ecosystems of the tropical Asian region. Its geographic presence is notably concentrated throughout the Malesia archipelago, where it plays a role in local biodiversity. Specifically, the species has been documented growing across the island of Borneo. Furthermore, its distribution extends to Jawa, highlighting its adaptability to different tropical island environments. These findings illustrate the widespread yet distinct range this plant maintains across Southeast Asian landscapes.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Alangium javanicum is a self-supporting plant characterized by its robust tree growth form. This sturdy structure allows it to stand independently within its natural habitat.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Compounds
Alangium javanicum is a plant species that serves as the natural source for several biologically significant compounds. Through the process of bioassay-guided fractionation of its crude extracts, researchers successfully identified a novel alkaloid known as javaniside. This specific chemical constituent is characterized by a unique monoterpenoid oxindole skeleton. Scientific studies have demonstrated that javaniside acts as an active principle contributing to DNA strand cleavage in the presence of copper ions. Furthermore, the absolute stereochemistry of this important molecule was successfully established through semisynthesis.
Conditions
Alangium javanicum contains specific alkaloids that actively mediate Cu2+-dependent DNA strand scission. Researchers utilized crude extracts from the plant to induce DNA strand breakage when in the presence of copper ions. Through bioassay-guided fractionation, the novel alkaloid javaniside was identified as a primary active principle contributing to this cleavage activity. This unique compound possesses an unusual monoterpenoid oxindole skeleton that facilitates the observed DNA damage. The identification and structural characterization of javaniside confirm its role in the plant's ability to trigger copper-dependent DNA scission.
Preparations
Alangium javanicum is prepared as crude $\text{CH}_2\text{Cl}_2\text{-MeOH}$ extracts for the purpose of studying its biochemical properties. These specific extracts were found to induce DNA strand breakage when in the presence of $\text{Cu}^{2+}$. Researchers utilized bioassay-guided fractionation on these prepared extracts to isolate their active principles. Through this process, the novel alkaloid javaniside was identified as a primary component contributing to the observed DNA cleavage activity. This methodological approach allowed for the successful isolation and structural analysis of the plant's bioactive constituents.