Aglaia perviridis
Aglaia perviridis · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Aglaia perviridis is a botanical species known for containing potent bioactive compounds such as episilvestrol, cyclopenta[b]benzofuran, and silvestrol. Researchers have focused on the plant's root and leaf components to explore their complex biological properties. By utilizing aqueous and ethyl acetate extracts, scientists can isolate these chemicals to study their significant cytotoxic activities. These specific preparations are being investigated for their potential therapeutic applications in treating critical medical conditions. Most notably, the plant shows promise in addressing physiological complications related to cerebral edema and ischemic stroke.
- Synonyms
- Aglaia Maiae · Aglaia Canarensis · 1 more
- Common names
- Not available
- Family
- Meliaceae
- Distribution
- Southern America
- Plant Parts
- Root · Leaf
Classification
Common Names
Aglaia perviridis is a remarkable plant known by a diverse array of regional and linguistic identifiers. In certain areas, it is commonly referred to by the names Bale Mauwa or G[ooj]i Xanh. Local populations also frequently use the term Sanu Lahasune to describe this specific species. Furthermore, it is recognized in Chinese contexts by the name 碧绿米仔兰. These varied common names highlight the plant's widespread presence across different cultural landscapes.
Sources: Catalogue of Life (COL)
Synonyms
Aglaia perviridis is a botanical species that encompasses several distinct taxonomic classifications within its history. Researchers have identified that this plant is closely linked to the synonym Aglaia canarensis. Furthermore, the species is also associated with the name Aglaia kingiana in various botanical records. Taxonomic studies further reveal that Aglaia maiae serves as another recognized synonym for this plant. Understanding these overlapping names is essential for maintaining accuracy in botanical documentation and research.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Aglaia perviridis is a distinct biological entity belonging to the vast kingdom Plantae. Within this expansive realm, the species is classified under the class Equisetopsida. It further resides within the order Sapindales, a group that showcases diverse botanical characteristics. This plant is a member of the genus Aglaia, which defines its specific structural lineage. Finally, its taxonomic placement is completed by its membership in the family Meliaceae.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Sapindales |
| Family | Meliaceae |
| Genus | Aglaia |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Aglaia perviridis is a diverse species with a broad geographical footprint spanning across various Asian regions. Its distribution includes temperate zones within China and South-Central China. The plant also thrives in tropical environments throughout the Indian Subcontinent, including specific areas like Assam and Bangladesh. Furthermore, its presence extends into the East Himalaya and throughout many parts of India. This wide range highlights the plant's adaptability to both temperate and tropical climates.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Aglaia perviridis is a self-supporting tree characterized by its sturdy and upright growth form. This species typically reaches a maximum height of 12 meters as it matures in its natural habitat. Its structural integrity allows it to stand firmly within the forest canopy.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Aglaia perviridis has proven to be a significant source of unique chemical compounds, particularly through the isolation of novel cyclopenta[b]benzofuran derivatives from its roots. Recent research conducted in Vietnam successfully identified several new structural analogues, including a derivative that exhibits notable biological potential. Specifically, the study highlighted that certain isolated compounds demonstrate potent cytotoxic activity against human cancer cell lines. Among the findings, compound 5 showed significant effectiveness against both HT-29 colon cancer and PC-3 prostate cancer cells. These results provide critical insights into the structural requirements necessary for developing cytotoxic agents within this specific class of plant-derived molecules.
Compounds
Aglaia perviridis is a tropical plant recognized for its rich production of bioactive compounds, including the pharmacological interest of silvestrol. Comprehensive phytochemical analyses of its roots have identified several novel flavagline derivatives, such as compounds 1a and 2a. Furthermore, the plant contains specific structural variations including 2b and 4a. These diverse chemical constituents contribute to the plant's significant therapeutic potential. Through these various relationships, the species serves as a vital source for studying complex natural products.
Conditions
Aglaia perviridis exhibits significant therapeutic potential by treating antineuroinflammatory activity through its flavagline-containing extracts. The plant also aids in the management of ischemic stroke by reducing cerebral infarct volume and alleviating cerebral edema in rat models. Furthermore, certain isolated compounds from the species, such as aglapervirisin A, induce cell cycle arrest at the G2/M-phase boundary in HepG2 cells. This same compound is also capable of treating HepG2 cells by inducing apoptosis. Collectively, these diverse biological activities highlight the complex medicinal properties of the plant.
Preparations
Aglaia perviridis is prepared as an aqueous extract to isolate unique cyclopenta[b]benzofuran derivatives from its roots. This specific aqueous preparation allowed for the identification of compound 5, which demonstrated cytotoxic activity against human colon and prostate cancer cell lines. Additionally, Aglaia perviridis is prepared as an ethyl acetate extract to study its therapeutic potential against ischemic stroke. This ethyl acetate extract, referred to as APE, contains total flavaglines that exhibit significant antineuroinflammatory activity. The use of these different extraction methods facilitates the isolation of diverse bioactive compounds from the plant.
Parts used
Aglaia perviridis is a tropical plant species that serves as a significant source of bioactive secondary metabolites. Scientific investigations have specifically identified the roots of this plant as a rich reservoir for diverse rocaglate derivatives and triterpenoids. These root-derived compounds, including various silvestrol analogs, have demonstrated impressive submicromolar potency against several human cancer cell lines. Furthermore, the leaves of Aglaia perviridis have been found to contain unique rocaglates, such as aglapervirisin A, which can induce apoptosis in HepG2 cells. By utilizing both the roots and leaves, researchers continue to uncover the complex chemical potential of this important botanical species.