conker tree
Aesculus hippocastanum · Accepted scientific name
Scientific literature: Very Extensive (808 studies) · ★★★★★
Conker tree, scientifically known as Aesculus hippocasstanum, is a deciduous species prized for its ornamental beauty and medicinal potential. Primarily recognized for its seeds, the plant contains aescin, a compound widely used in pharmacology to treat venous insufficiency, reduce swelling, and improve circulation in patients with chronic vascular issues.
Names
Common Names
- conker-tree
- horse-chestnut
- European horse-chestnut
- Horse Chestnut
- common horsechestnut
- conker tree
- European horse chestnut
- Spanish chestnut
- White Horse Chestnut
- buckeye
Regional and Traditional Names
Spanish:
- Castaño de Indias común
- Castaña borde
- Castaño caballuno
- Castañas pilongas
- Castaño de Indias
- Castaño falso
- Castano de Indias
- Castaño loco
- Castaña pilonga
- Castaño borde
- Castaño de caballo
- Castaño de sombra
- Castaño caballar
- Castañera borde
- Castaña de Indias
- Castaña loca
- castaño-de-indias
- castaño-loco
- castaño de Indias
- Castaño de la India
German:
- Gewöhnliche Rosskastanie
- Gemeine Rosskastanie
- Gewöhnliche Roßkastanie
- Weiße Rosskastanie
- Rosskastanie
- gewöhnliche Rosskastanie
- Rosskastanie
- Gemeine Rosskastanie
- Weiße Rosskastanie
French:
- Marronnier commun
- Marronnier d'Inde
- Marronier d'inde
- Marronier
- Maronnier
- marronnier-commun
- mmarronnier-d'inde
- marronnier commun
- marronnier d’Inde
- marronnier
- marronnier d'Inde
- Marronier commun
Scientific Names
Accepted name
Aesculus hippocastanumSynonyms
- Aesculus hippocastanum f. beaumanii
- Aesculus hippocastanum f. pendula
- Pawia hippocastanum
- Aesculus hippocastanum var. pendula
- Aesculus asplenifolia
- Aesculus hippocastanum f. baumannii
- Aesculus hippocastanum f. memmingeri
- Aesculus hippocastanum var. beaumanii
- Aesculus hippocastanum var. luteovariegatum
- Aesculus memmingeri
- Aesculus hippocastanum var. variegata
- Aesculus procera
- Aesculus hippocastanum f. luteovariegatum
- Aesculus septenata
- Hippocastanum aesculus
- Aesculus hippocastanum f. albovariegatum
- Hippocastanum vulgare
- Aesculus hippocastanum var. aureovariegata
- Aesculus hippocastanum var. albovariegatum
- Aesculus hippocastanum var. argenteovariegata
- Aesculus hippocastanum var. laciniata
- Aesculus hippocastanum var. incisa
- Aesculus hippocastanum f. laciniata
- Aesculus hippocastanum var. pyramidalis
- Aesculus hippocastanum f. pyramidalis
- Aesculus hippocastanum var. umbraculifera
- Aesculus hippocastanum f. umbraculifera
Taxonomical Classification
This plant, known scientifically as Aesculus hippocastanum, belongs to the kingdom Plantae and the phylum Streptophyta. It is further classified within the class Equisetopsida and the subclass Magnoliidae, falling under the order Sapindales. Finally, it is a member of the family Sapindaceae within the genus Aesculus.
| Rank | Classification | Source |
|---|---|---|
| Kingdom | Plantae | WCVP |
| Phylum | Streptophyta | WCVP |
| Class | Equisetopsida | WCVP |
| Subclass | Magnoliidae | WCVP |
| Order | Sapindales | WCVP |
| Family | Sapindaceae | WCVP |
| Genus | Aesculus | WCVP |
Distribution
This plant exhibits a broad distribution across several key regions of the European continent. In Northern Europe, its presence is documented in both Great Britain and Ireland. Moving toward the center of the continent, the species is also found within Middle Europe. Specifically, it can be located in the territories of Austria and Belgium. Finally, its geographical range extends further into Middle Europe through Czechia and Slovakia.
| Region | Area | Source |
|---|---|---|
| Northern Europe | Great Britain | WCVP |
| Northern Europe | Ireland | WCVP |
| Middle Europe | Austria | WCVP |
| Middle Europe | Belgium | WCVP |
| Middle Europe | Czechia-Slovakia | WCVP |
| Middle Europe | Germany | WCVP |
| Middle Europe | Hungary | WCVP |
| Middle Europe | Poland | WCVP |
| Middle Europe | Switzerland | WCVP |
| Southwestern Europe | France | WCVP |
Plant Parts
This plant, commonly known as the horse chestnut, utilizes its fruits as the primary source of its medicinal compounds. These fruits are distinctive, thick-shelled capsules that typically contain one to three large, shiny brown seeds, often referred to as conkers. Within these fruits, the seeds contain high concentrations of aescin, a saponin used therapeutically to treat venous insufficiency and inflammation.| Plant Part | Sources | Consensus |
|---|---|---|
| fruit | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
Chemicals
Aesculus hippocastanum has 154 reported phytochemicals identified across 1 scientific publications and several other databases. The most consistently reported chemicals include Aescin, Escin, Esculin, Castaprenol 12, Epicatechin.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Aescin | 4 supporting sources | ★★☆☆☆ |
| Escin | 3 supporting sources | ★★☆☆☆ |
| Esculin | 3 supporting sources | ★★☆☆☆ |
| Castaprenol 12 | 2 supporting sources | ★☆☆☆☆ |
| Epicatechin | 2 supporting sources | ★☆☆☆☆ |
| Fraxin | 2 supporting sources | ★☆☆☆☆ |
| RUTIN | 2 supporting sources | ★☆☆☆☆ |
| allantoin | 2 supporting sources | ★☆☆☆☆ |
| beta-Aescin | 2 supporting sources | ★☆☆☆☆ |
| kaempferol | 2 supporting sources | ★☆☆☆☆ |
Aescin
- Dr. Duke
- Journal of chromatography. A
- Methods and findings in experimental and clinical pharmacology
- Plants (Basel, Switzerland)
Escin
- Dr. Duke
- Natural product research
- Environmental toxicology
Esculin
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
- Journal of basic and clinical physiology and pharmacology
Castaprenol 12
- Dr. Duke
- The Biochemical journal
Epicatechin
- Dr. Duke
- Journal of basic and clinical physiology and pharmacology
Fraxin
- Dr. Duke
- Journal of basic and clinical physiology and pharmacology
RUTIN
- Dr. Duke
- Journal of pharmaceutical and biomedical analysis
allantoin
- Dr. Duke
- Iranian journal of pharmaceutical research : IJPR
beta-Aescin
- Dr. Duke
- Methods and findings in experimental and clinical pharmacology
kaempferol
- Dr. Duke
- Journal of basic and clinical physiology and pharmacology
Activities
Aesculus hippocastanum has 561 reported activities identified across 1 scientific publications and several other databases. The most consistently reported activities include Antiedemic, 11B-HSD-Inhibitor, 5-Alpha-Reductase-Inhibitor, 5-HT-Inhibitor, 5-Lipoxygenase-Inhibitor.
Most Reported Activities
| Activity | Sources | Consensus |
|---|---|---|
| Antiedemic | Dr. Duke (and other 2 sources) | ★☆☆☆☆ |
| 11B-HSD-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| 5-Alpha-Reductase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| 5-HT-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| 5-Lipoxygenase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ACE-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ACTH-genic | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| AChE-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| ATPase-Inhibitor | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
| Absorbent | Dr. Duke (and other 1 sources) | ★☆☆☆☆ |
Medicinal Uses
Aesculus hippocastanum has 8 reported medicinal uses identified across 1 scientific publications and several other databases. The most consistently reported uses include angiogenesis, bleeding, cancer, hepatocellular carcinoma, liver cancer.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| angiogenesis | Planta medica (and other 1 sources) | ★☆☆☆☆ |
| bleeding | Cureus (and other 1 sources) | ★☆☆☆☆ |
| cancer | Naunyn-Schmiedeberg's archives of pharmacology (and other 1 sources) | ★☆☆☆☆ |
| hepatocellular carcinoma | Environmental toxicology (and other 1 sources) | ★☆☆☆☆ |
| liver cancer | Environmental toxicology (and other 1 sources) | ★☆☆☆☆ |
| pain | Cureus (and other 1 sources) | ★☆☆☆☆ |
| platelet aggregation | Seminars in thrombosis and hemostasis (and other 1 sources) | ★☆☆☆☆ |
| varicose veins | Dermatologic therapy (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| acid hydrolysis product of a crude saponin fraction | Journal of natural products (and other 1 sources) | ★☆☆☆☆ |
| plant extracts | Life (Basel, Switzerland) (and other 1 sources) | ★☆☆☆☆ |