wolf's bane
Aconitum · Accepted scientific name
Scientific literature: Moderate (101 studies) · ★★★☆☆
Wolf's bane, scientifically known as Aconitum, is a genus of striking flowering perennials renowned for their beauty and extreme toxicity. While historically utilized in traditional medicine for its potent alkaloids, its high level of poison requires immense caution, as even minor contact can lead to severe, life-threatening systemic effects.
Names and Synonyms
Common Names
- monkshood
- wolfsbane
- Monk's-Hood
- Aconite
- Aconites
- Monks-Hood
- Monkshoods
Scientific Names
Accepted name
AconitumSynonyms
- Anthora
- Nirbisia
- Napellus
- Lycoctonum
- Cammarum
Regional and Traditional Names
Spanish:
- Acónito
- Aconito
- Acónito
German:
- Eisenhut
- Wolfswurz
- Akonit
French:
- Aconit
- Aconits
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and is classified under the phylum Streptophyta and the class Equisetopsida. Within the subclass Magnoliidae, it is further categorized under the order Ranunculales and the family Ranunculaceae. Finally, its specific taxonomic designation is placed within the genus Aconitum.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Ranunculales |
| Family | Ranunculaceae |
| Genus | Aconitum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific distribution pattern across the northern regions of Europe. It can be found growing in the natural landscapes of Denmark and Finland. Additionally, the species is present within the territories of Great Britain. Its range also extends to the Scandinavian countries of Norway and Sweden. Consequently, the geographical presence of Aconitum is concentrated in these northernmost European locations.
| Region | Area |
|---|---|
| Northern Europe | Denmark |
| Northern Europe | Finland |
| Northern Europe | Great Britain |
| Northern Europe | Norway |
| Northern Europe | Sweden |
| Middle Europe | Austria |
| Middle Europe | Belgium |
| Middle Europe | Czechia-Slovakia |
| Middle Europe | Germany |
| Middle Europe | Hungary |
Sources: The World Checklist of Vascular Plants (WCVP)
Plant Parts
Aconitum has 2 reported plant parts identified across 6 scientific publications and several other databases that are studied for medicinal purposes. The most consistently reported plant part include root, flower.
| Plant part | Supporting sources | Consensus |
|---|---|---|
| Root | 5 supporting sources | ★★★☆☆ |
| Flower | 1 supporting sources | ★☆☆☆☆ |
Root
- Journal of pharmacobio-dynamics
- Journal of ethnopharmacology
- The Journal of pharmacy and pharmacology
- Plant physiology and biochemistry : PPB
- Fa yi xue za zhi
Flower
- MMWR. Morbidity and mortality weekly report
Chemicals
Aconitum has 25 reported phytochemicals identified across 6 scientific publications and several other databases. The most consistently reported chemicals include aconitine, Hypaconitine, lappaconitine, Flavonoids, 2,5-Dihydroxy benzoic acid.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| aconitine | 15 supporting sources | ★★★★★ |
| Hypaconitine | 5 supporting sources | ★★★☆☆ |
| lappaconitine | 3 supporting sources | ★★☆☆☆ |
| Flavonoids | 2 supporting sources | ★☆☆☆☆ |
| 2,5-Dihydroxy benzoic acid | 1 supporting sources | ★☆☆☆☆ |
| 3-Acetylaconitine | 1 supporting sources | ★☆☆☆☆ |
| 6-Benzoylheteratisine | 1 supporting sources | ★☆☆☆☆ |
| ACONITE | 1 supporting sources | ★☆☆☆☆ |
| Aconine | 1 supporting sources | ★☆☆☆☆ |
| Ajacine | 1 supporting sources | ★☆☆☆☆ |
aconitine
- European journal of pharmacology
- Phytochemical analysis : PCA
- Legal medicine (Tokyo, Japan)
- Toxins
- Frontiers in medicine
View 10 additional sources
- Toxicology and applied pharmacology
- Journal of applied toxicology : JAT
- Scientific reports
- Molecules (Basel, Switzerland)
- Analytica chimica acta
- Medicine
- Journal of chromatographic science
- Frontiers in pharmacology
- Journal of forensic sciences
- Biochemical pharmacology
Hypaconitine
- Phytochemical analysis : PCA
- Legal medicine (Tokyo, Japan)
- Analytica chimica acta
- Journal of chromatographic science
- Journal of forensic sciences
lappaconitine
- European journal of pharmacology
- Molecules (Basel, Switzerland)
- Biochemical pharmacology
Flavonoids
- The Journal of pharmacy and pharmacology
- Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
2,5-Dihydroxy benzoic acid
- Fa yi xue za zhi
3-Acetylaconitine
- Biochemical pharmacology
6-Benzoylheteratisine
- European journal of pharmacology
ACONITE
- MMWR. Morbidity and mortality weekly report
Aconine
- Frontiers in pharmacology
Ajacine
- European journal of pharmacology
Activities
Aconitum has 7 reported activities identified across 6 scientific publications and several other databases. The most consistently reported activities include Analgesic, Antiinflammatory, Antiarrhythmic, Antiproliferative, Antitumor.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Analgesic | 3 supporting sources | ★★☆☆☆ |
| Antiinflammatory | 2 supporting sources | ★☆☆☆☆ |
| Antiarrhythmic | 1 supporting sources | ★☆☆☆☆ |
| Antiproliferative | 1 supporting sources | ★☆☆☆☆ |
| Antitumor | 1 supporting sources | ★☆☆☆☆ |
| Cardiotoxic | 1 supporting sources | ★☆☆☆☆ |
| Neurotoxic | 1 supporting sources | ★☆☆☆☆ |
Analgesic
- Chemistry & biodiversity
- Molecules (Basel, Switzerland)
- Journal of ethnopharmacology
Antiinflammatory
- Journal of pharmacobio-dynamics
- Journal of ethnopharmacology
Antiarrhythmic
- Chemistry & biodiversity
Antiproliferative
- Journal of natural medicines
Antitumor
- Chemistry & biodiversity
Cardiotoxic
- Journal of forensic sciences
Neurotoxic
- Journal of forensic sciences
Medicinal Uses
Aconitum has 26 reported medicinal uses identified across 6 scientific publications and several other databases. The most consistently reported uses include pain, inflammation, analgesic, cardiac arrest, Arrhythmia.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| pain | Journal of pharmaceutical and biomedical analysis (and other 4 sources) | ★★☆☆☆ |
| inflammation | Journal of pharmaceutical and biomedical analysis (and other 3 sources) | ★★☆☆☆ |
| analgesic | Chemistry & biodiversity (and other 2 sources) | ★☆☆☆☆ |
| cardiac arrest | Frontiers in medicine (and other 2 sources) | ★☆☆☆☆ |
| Arrhythmia | Journal of pharmaceutical and biomedical analysis (and other 1 sources) | ★☆☆☆☆ |
| acute kidney injury | International immunopharmacology (and other 1 sources) | ★☆☆☆☆ |
| adjuvant arthritis | Journal of pharmacobio-dynamics (and other 1 sources) | ★☆☆☆☆ |
| analgesia | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| breast cancer | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica (and other 1 sources) | ★☆☆☆☆ |
| cardiogenic shock | Frontiers in medicine (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| Aconitum crude drugs | Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials (and other 1 sources) | ★☆☆☆☆ |
| homemade alcoholic beverage | MMWR. Morbidity and mortality weekly report (and other 1 sources) | ★☆☆☆☆ |
| medicinal liquor | Journal of forensic sciences (and other 1 sources) | ★☆☆☆☆ |
| processing | Frontiers in pharmacology (and other 1 sources) | ★☆☆☆☆ |