Aconitum richardsonianum var. pseudosessiliflorum

Aconitum richardsonianum var. pseudosessiliflorum · Accepted scientific name

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Aconitum richardsonianum var. pseudosessiliflorum is a distinctive botanical variety known for its complex chemical composition. Scientific investigations into its roots have identified several potent alkaloids, including 3-Acetylaconitine, Delelatine, ISOATISINE, and Nordhagenine A. Researchers frequently utilize specific preparation methods, such as chloroform extraction and ethanol extracts, to isolate these bioactive compounds. The resulting residues from these processes provide valuable insights into the plant's underlying chemical profile. Understanding these root-derived substances is essential for studying the pharmacological potential of this specific taxon.

Quick facts
Synonyms
Aconitum Pseudosessiliflorum
Common names
Not available
Family
Ranunculaceae
Distribution
Pacific
Plant Parts
Root

Classification

Common Names

Aconitum richardsonianum var. pseudosessiliflorum is a specialized botanical variety recognized by several distinct regional identifiers. In certain contexts, it is commonly referred to by the name 伏毛直序乌. It is also frequently known as 细叶草乌, a name that highlights its specific morphological characteristics. These various common names help botanists and local practitioners distinguish the plant within its natural habitat. Understanding these linguistic relationships is essential for accurate identification and study of this specific taxon.

Sources: Catalogue of Life (COL)

Synonyms

Aconitum richardsonianum var. pseudosessiliflorum is a distinct botanical entity within its genus. In many scientific records, this particular variety is also identified by its synonym, Aconitum pseudosessiliflorum. Understanding these taxonomic relationships is essential for researchers tracking the plant's distribution and characteristics. Such nomenclature shifts often reflect evolving studies into the genetic and morphological nuances of the species. Consequently, recognizing both names ensures consistency across diverse botanical databases and field studies.

Sources: The World Checklist of Vascular Plants (WCVP)

Taxonomy

Aconitum richardsonianum var. pseudosessiliflorum is a specialized plant belonging to the vast kingdom Plantae. Within this biological hierarchy, it is classified under the class Equisetopsida. This variety falls specifically into the order Ranunculales, showcasing its evolutionary connections. It is a member of the Ranunculaceae family, a group known for its diverse botanical characteristics. Ultimately, this species is defined by its placement within the distinctive genus Aconitum.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Ranunculales
Family Ranunculaceae
Genus Aconitum

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

Geographic Regions

Aconitum richardsonianum var. pseudosessiliflorum is a distinct botanical variety primarily found within the Asia-Temperate region. Its geographic range is concentrated in specific high-altitude areas, particularly throughout the vast landscapes of China. Within these territories, the plant shows a notable presence in the unique environmental conditions of Tibet. This specialized distribution highlights the plant's adaptation to the rugged and diverse climates found in these mountainous zones. Understanding its localized habitat is essential for studying the ecological patterns of this particular taxon.

Sources: The World Checklist of Vascular Plants (WCVP)

Identification

Biological Activities

Compounds

Aconitum richardsonianum var. pseudosessiliflorum is a Tibetan medicinal plant that serves as a rich source of various diterpenoid alkaloids. Chemical investigations into the plant's roots have successfully isolated several significant compounds. Specifically, the plant contains 3-acetylaconitine, delelatine, and isoatisine. Furthermore, researchers have identified the presence of both nordhagenine A and yunaconitine within its chemical profile. These findings highlight the complex phytochemical makeup of this specific variety.

Conditions

Aconitum richardsonianum var. pseudosessiliflorum contains diterpenoid alkaloids that demonstrate significant cytotoxic potential. Researchers extracted chemical constituents from the roots of this Tibetan medicinal plant to isolate several specific compounds. Among these isolated substances, delelatine emerged as a particularly potent agent. This specific compound exhibited significant cytotoxic activity against the human tumor cell line P388. The study recorded an IC50 value of 4.36 μM for delelatine in its treatment of these cancer cells.

Preparations

Aconitum richardsonianum var. pseudosessiliflorum is prepared as roots to begin the chemical investigation of its constituents. These roots undergo a process to be prepared as ethanol extracts through extraction with 90% EtOH at room temperature. The resulting ethanol extracts are concentrated under reduced pressure to be prepared as residue. This residue is then suspended in water and successively partitioned to be prepared as a chloroform extraction. Finally, this chloroform extraction is isolated and purified using silica gel and Sephadex LH-20 column chromatography.

Parts used

Aconitum richardsonianum var. pseudosessiliflorum serves as a significant subject in the study of Tibetan medicinal plants. Researchers focused their investigation on the plant's root, which underwent a rigorous extraction process using 90% ethanol. Through various purification methods like silica gel and Sephadex LH-20 column chromatography, several key chemical constituents were successfully isolated. These include specific diterpenoid alkaloids such as delelatine, isodelpheline, and yunaconitine. Notably, the compound delelatine demonstrated significant cytotoxic activity against the human P388 tumor cell line.