arrow-poison-tree
Acokanthera schimperi · Accepted scientific name
Scientific literature: Very Sparse (21 studies) · ★☆☆☆☆
arrow-poison-tree, scientifically known as Acokanthera schimperi, is a potent medicinal plant native to East Africa. Renowned for its highly toxic cardiac glycosides, it has historically been used to create lethal hunting arrows. Today, researchers study its chemical compounds for potential pharmacological applications in treating cardiovascular diseases and regulating heart rhythms.
- Family
- Apocynaceae
- Native range
- Africa
- Parts used
- Not available
- Common names
- Arrow-Poison-Tree · Common-Poisonbush
- Scientific synonyms
- Carissa Schimperi · Acokanthera Schimperi Var. Ouabaio · 7 more
Names and Synonyms
Common Names
- arrow-poison-tree
- common-poisonbush
Scientific Names
Accepted name
Acokanthera schimperiSynonyms
- Carissa schimperi
- Acokanthera schimperi var. ouabaio
- Carissa friesiorum
- Arduina schimperi
- Carissa inepta
- Acokanthera ouabaio
- Carissa deflersii
- Acokanthera deflersii
- Acokanthera friesiorum
Regional and Traditional Names
Spanish:
- Carissa friesiorum
- Carissa deflersii
- Acokanthera scabra
- Carissa inepta
- Carissa schimperi
- Acokanthera deflersii
- Acokanthera ouabaio
- Arduina schimperi
- Acokanthera abyssinica
- Acokanthera friesiorum
German:
- Pfeilspitzen-Schöngift
French:
- Acokanthera abyssinica
Sources: Wikidata, Catalogue of Life
Taxonomical Classification
This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Gentianaales, it is classified under the family Apocynaceae. Finally, its specific taxonomic placement is within the genus Acokanthera.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Gentianales |
| Family | Apocynaceae |
| Genus | Acokanthera |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
This plant exhibits a specific geographical distribution across several regions of the African continent. In West-Central Tropical Africa, it can be found within the borders of Rwanda and the Democratic Republic of the Congo. Moving toward the east, its range extends into Northeast Tropical Africa. Within this northeastern region, the species is documented in Djibouti and Eritrea. Finally, its presence is also confirmed in the highland landscapes of Ethiopia.
| Region | Area |
|---|---|
| West-Central Tropical Africa | Rwanda |
| West-Central Tropical Africa | DR Congo |
| Northeast Tropical Africa | Djibouti |
| Northeast Tropical Africa | Eritrea |
| Northeast Tropical Africa | Ethiopia |
| Northeast Tropical Africa | Socotra |
| Northeast Tropical Africa | Somalia |
| East Tropical Africa | Kenya |
| East Tropical Africa | Tanzania |
| East Tropical Africa | Uganda |
Sources: The World Checklist of Vascular Plants (WCVP)
Botanical Identification
Life history
The life history of Acokanthera schimperi is characterized by a perennial lifecycle, allowing the plant to persist across multiple growing seasons. Functioning as a phanerophyte, it maintains its buds well above the ground, typically manifesting as a woody shrub or small tree. Its foliage remains evergreen, ensuring a continuous presence of photosynthetic tissue throughout the year. Furthermore, its structural classification includes traits of a nanophanerophyte, reflecting its specific growth habit and stature within its ecological niche.
- Deciduousness :
- evergreen
- Life form :
- nanophanerophyte
- Life form :
- phanerophyte
- Lifecycle :
- perennial
Morphology
The morphology of Acokanthera schimperi is characterized by a woody growth habit that can manifest as both a tree and a shrub. This species typically reaches a mean plant height of approximately 9 meters. It functions as an independent organism rather than a parasite and maintains a terrestrial life form rather than being an epiphyte. In terms of its structural support, the plant is classified as self-supporting, meaning it does not rely on other structures to climb.
- Climber :
- self-supporting
- Epiphyte :
- terrestrial
- Growth form :
- tree
- Growth form :
- shrub
- Parasite :
- independent
- Plant height mean:
- 9 m
- Woodiness :
- woody
Physiology
The physiology of Acokanthera schimperi is characterized by complex metabolic processes centered on the synthesis and sequestration of highly potent cardiac glycosides, which serve as a sophisticated chemical defense mechanism against herbivory. Its metabolic pathways are specialized for the production of toxic secondary metabolites, primarily ouabain, which act by inhibiting the sodium-potassium ATPase pump in cellular membranes. From a nutritional standpoint, the plant does not engage in symbiotic relationships with diazotrophic bacteria to facilitate atmospheric nitrogen conversion; therefore, it is not a nitrogen fixer. This lack of nitrogen-fixing capability means the plant relies entirely on the uptake of available nitrates and ammonium ions from the soil through its root system to support its protein synthesis and overall growth. Its physiological functions are optimized for survival in specific ecological niches where the management of nitrogen resources and the deployment of chemical deterrents are critical for maintaining metabolic homeostasis and deterring predation.
- Nitrogen fixer :
- no
Reproduction
The reproduction of Acokanthera schimperi is driven by a biotic pollination syndrome, primarily facilitated through interactions with animal vectors. Specifically, the plant relies on insects for pollination, with bees identified as a key functional group in the transfer of pollen. Following successful fertilization, the plant produces seeds that exhibit significant morphological variation in weight. The seed mass ranges from a minimum of 0.0203 g to a maximum of 0.167 g, with an average seed mass measured at approximately 0.09365 g.
- Pollination syndrome :
- insect
- Pollination syndrome :
- bee
- Pollination syndrome :
- biotic
- Seed mass max:
- 0.167 g
- Seed mass mean:
- 0.09365 g
- Seed mass min:
- 0.0203 g
Sources: Global Inventory of Floras and Traits (GIFT)
Chemicals
Acokanthera schimperi has 7 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include Acolongifloroside G, Acolongifloroside H, Acovenoside A, Flavonoids, Sulfur Compounds.
| Chemical | Supporting sources | Consensus |
|---|---|---|
| Acolongifloroside G | 1 supporting sources | ★☆☆☆☆ |
| Acolongifloroside H | 1 supporting sources | ★☆☆☆☆ |
| Acovenoside A | 1 supporting sources | ★☆☆☆☆ |
| Flavonoids | 1 supporting sources | ★☆☆☆☆ |
| Sulfur Compounds | 1 supporting sources | ★☆☆☆☆ |
| Tannins | 1 supporting sources | ★☆☆☆☆ |
| ouabain | 1 supporting sources | ★☆☆☆☆ |
Acolongifloroside G
- Dr. Duke
Acolongifloroside H
- Dr. Duke
Acovenoside A
- Dr. Duke
Flavonoids
- BMC plant biology
Sulfur Compounds
- BMC plant biology
Tannins
- BMC plant biology
ouabain
- Dr. Duke
Activities
Acokanthera schimperi has 9 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include Antiarrhythmic, Anticarcinomic, Antiproliferative, Antiviral, Cardioactive.
| Activity | Supporting sources | Consensus |
|---|---|---|
| Antiarrhythmic | 1 supporting sources | ★☆☆☆☆ |
| Anticarcinomic | 1 supporting sources | ★☆☆☆☆ |
| Antiproliferative | 1 supporting sources | ★☆☆☆☆ |
| Antiviral | 1 supporting sources | ★☆☆☆☆ |
| Cardioactive | 1 supporting sources | ★☆☆☆☆ |
| Cardiotonic | 1 supporting sources | ★☆☆☆☆ |
| Diuretic | 1 supporting sources | ★☆☆☆☆ |
| Emetic | 1 supporting sources | ★☆☆☆☆ |
| Memorilytic | 1 supporting sources | ★☆☆☆☆ |
Antiarrhythmic
- Dr. Duke
Anticarcinomic
- Dr. Duke
Antiproliferative
- Fitoterapia
Antiviral
- Dr. Duke
Cardioactive
- Dr. Duke
Cardiotonic
- Dr. Duke
Diuretic
- Dr. Duke
Emetic
- Dr. Duke
Memorilytic
- Dr. Duke
Medicinal Uses
Acokanthera schimperi has 4 reported medicinal uses identified across 0 scientific publications and several other databases. The most consistently reported uses include Aspergillus niger, cancer, influenza A virus, trypanosomes.
Most Reported Uses
| Use | Sources | Consensus |
|---|---|---|
| Aspergillus niger | BMC plant biology (and other 1 sources) | ★☆☆☆☆ |
| cancer | Fitoterapia (and other 1 sources) | ★☆☆☆☆ |
| influenza A virus | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| trypanosomes | Zeitschrift fur Naturforschung. C, Journal of biosciences (and other 1 sources) | ★☆☆☆☆ |
Preparations
| Preparations | Sources | Consensus |
|---|---|---|
| 80% methanol extracts | Molecules (Basel, Switzerland) (and other 1 sources) | ★☆☆☆☆ |
| 80% methanolic extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| Crude extracts | BMC plant biology (and other 1 sources) | ★☆☆☆☆ |
| Hydroalcoholic extracts | Journal of ethnopharmacology (and other 1 sources) | ★☆☆☆☆ |
| absolute methanol | Asian Pacific journal of tropical biomedicine (and other 1 sources) | ★☆☆☆☆ |
| essential oils | BMC plant biology (and other 1 sources) | ★☆☆☆☆ |
| water | Asian Pacific journal of tropical biomedicine (and other 1 sources) | ★☆☆☆☆ |