arrow-poison-tree

Acokanthera schimperi · Accepted scientific name

Scientific literature: Very Sparse (21 studies) · ★☆☆☆☆

arrow-poison-tree, scientifically known as Acokanthera schimperi, is a potent medicinal plant native to East Africa. Renowned for its highly toxic cardiac glycosides, it has historically been used to create lethal hunting arrows. Today, researchers study its chemical compounds for potential pharmacological applications in treating cardiovascular diseases and regulating heart rhythms.

Family
Apocynaceae
Native range
Africa
Parts used
Not available
Common names
Arrow-Poison-Tree · Common-Poisonbush
Scientific synonyms
Carissa Schimperi · Acokanthera Schimperi Var. Ouabaio · 7 more

Names and Synonyms

Common Names

Scientific Names

Accepted name

Acokanthera schimperi

Synonyms

Regional and Traditional Names

Spanish:

  • Carissa friesiorum
  • Carissa deflersii
  • Acokanthera scabra
  • Carissa inepta
  • Carissa schimperi
  • Acokanthera deflersii
  • Acokanthera ouabaio
  • Arduina schimperi
  • Acokanthera abyssinica
  • Acokanthera friesiorum

German:

  • Pfeilspitzen-Schöngift

French:

  • Acokanthera abyssinica

Sources: Wikidata, Catalogue of Life

Taxonomical Classification

This plant belongs to the kingdom Plantae and the phylum Streptophyta, falling under the class Equisetopsida and subclass Magnoliidae. Within the order Gentianaales, it is classified under the family Apocynaceae. Finally, its specific taxonomic placement is within the genus Acokanthera.

Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Gentianales
Family Apocynaceae
Genus Acokanthera

Sources: The World Checklist of Vascular Plants (WCVP)

Distribution

This plant exhibits a specific geographical distribution across several regions of the African continent. In West-Central Tropical Africa, it can be found within the borders of Rwanda and the Democratic Republic of the Congo. Moving toward the east, its range extends into Northeast Tropical Africa. Within this northeastern region, the species is documented in Djibouti and Eritrea. Finally, its presence is also confirmed in the highland landscapes of Ethiopia.

Region Area
West-Central Tropical Africa Rwanda
West-Central Tropical Africa DR Congo
Northeast Tropical Africa Djibouti
Northeast Tropical Africa Eritrea
Northeast Tropical Africa Ethiopia
Northeast Tropical Africa Socotra
Northeast Tropical Africa Somalia
East Tropical Africa Kenya
East Tropical Africa Tanzania
East Tropical Africa Uganda

Sources: The World Checklist of Vascular Plants (WCVP)

Botanical Identification

Life history

The life history of Acokanthera schimperi is characterized by a perennial lifecycle, allowing the plant to persist across multiple growing seasons. Functioning as a phanerophyte, it maintains its buds well above the ground, typically manifesting as a woody shrub or small tree. Its foliage remains evergreen, ensuring a continuous presence of photosynthetic tissue throughout the year. Furthermore, its structural classification includes traits of a nanophanerophyte, reflecting its specific growth habit and stature within its ecological niche.

Deciduousness :
evergreen
Life form :
nanophanerophyte
Life form :
phanerophyte
Lifecycle :
perennial

Morphology

The morphology of Acokanthera schimperi is characterized by a woody growth habit that can manifest as both a tree and a shrub. This species typically reaches a mean plant height of approximately 9 meters. It functions as an independent organism rather than a parasite and maintains a terrestrial life form rather than being an epiphyte. In terms of its structural support, the plant is classified as self-supporting, meaning it does not rely on other structures to climb.

Climber :
self-supporting
Epiphyte :
terrestrial
Growth form :
tree
Growth form :
shrub
Parasite :
independent
Plant height mean:
9 m
Woodiness :
woody

Physiology

The physiology of Acokanthera schimperi is characterized by complex metabolic processes centered on the synthesis and sequestration of highly potent cardiac glycosides, which serve as a sophisticated chemical defense mechanism against herbivory. Its metabolic pathways are specialized for the production of toxic secondary metabolites, primarily ouabain, which act by inhibiting the sodium-potassium ATPase pump in cellular membranes. From a nutritional standpoint, the plant does not engage in symbiotic relationships with diazotrophic bacteria to facilitate atmospheric nitrogen conversion; therefore, it is not a nitrogen fixer. This lack of nitrogen-fixing capability means the plant relies entirely on the uptake of available nitrates and ammonium ions from the soil through its root system to support its protein synthesis and overall growth. Its physiological functions are optimized for survival in specific ecological niches where the management of nitrogen resources and the deployment of chemical deterrents are critical for maintaining metabolic homeostasis and deterring predation.

Nitrogen fixer :
no

Reproduction

The reproduction of Acokanthera schimperi is driven by a biotic pollination syndrome, primarily facilitated through interactions with animal vectors. Specifically, the plant relies on insects for pollination, with bees identified as a key functional group in the transfer of pollen. Following successful fertilization, the plant produces seeds that exhibit significant morphological variation in weight. The seed mass ranges from a minimum of 0.0203 g to a maximum of 0.167 g, with an average seed mass measured at approximately 0.09365 g.

Pollination syndrome :
insect
Pollination syndrome :
bee
Pollination syndrome :
biotic
Seed mass max:
0.167 g
Seed mass mean:
0.09365 g
Seed mass min:
0.0203 g

Sources: Global Inventory of Floras and Traits (GIFT)

Chemicals

Acokanthera schimperi has 7 reported phytochemicals identified across 0 scientific publications and several other databases. The most consistently reported chemicals include Acolongifloroside G, Acolongifloroside H, Acovenoside A, Flavonoids, Sulfur Compounds.

Chemicals reported in Acokanthera schimperi
Chemical Supporting sources Consensus
Acolongifloroside G 1 supporting sources ★☆☆☆☆
Acolongifloroside H 1 supporting sources ★☆☆☆☆
Acovenoside A 1 supporting sources ★☆☆☆☆
Flavonoids 1 supporting sources ★☆☆☆☆
Sulfur Compounds 1 supporting sources ★☆☆☆☆
Tannins 1 supporting sources ★☆☆☆☆
ouabain 1 supporting sources ★☆☆☆☆

Acolongifloroside G

  1. Dr. Duke

Acolongifloroside H

  1. Dr. Duke

Acovenoside A

  1. Dr. Duke

Flavonoids

  1. BMC plant biology

Sulfur Compounds

  1. BMC plant biology

Tannins

  1. BMC plant biology

ouabain

  1. Dr. Duke

Activities

Acokanthera schimperi has 9 reported activities identified across 0 scientific publications and several other databases. The most consistently reported activities include Antiarrhythmic, Anticarcinomic, Antiproliferative, Antiviral, Cardioactive.

Activities reported in Acokanthera schimperi
Activity Supporting sources Consensus
Antiarrhythmic 1 supporting sources ★☆☆☆☆
Anticarcinomic 1 supporting sources ★☆☆☆☆
Antiproliferative 1 supporting sources ★☆☆☆☆
Antiviral 1 supporting sources ★☆☆☆☆
Cardioactive 1 supporting sources ★☆☆☆☆
Cardiotonic 1 supporting sources ★☆☆☆☆
Diuretic 1 supporting sources ★☆☆☆☆
Emetic 1 supporting sources ★☆☆☆☆
Memorilytic 1 supporting sources ★☆☆☆☆

Antiarrhythmic

  1. Dr. Duke

Anticarcinomic

  1. Dr. Duke

Antiproliferative

  1. Fitoterapia

Antiviral

  1. Dr. Duke

Cardioactive

  1. Dr. Duke

Cardiotonic

  1. Dr. Duke

Diuretic

  1. Dr. Duke

Emetic

  1. Dr. Duke

Memorilytic

  1. Dr. Duke

Conditions

Acokanthera schimperi has 4 reported investigations on conditions identified across 0 scientific publications and several other databases. The most consistently reported conditions include Aspergillus niger, cancer, influenza A virus, trypanosomes.

Conditions investigated for Acokanthera schimperi
Condition Supporting sources Consensus
Aspergillus niger 1 supporting sources ★☆☆☆☆
Cancer 1 supporting sources ★☆☆☆☆
Influenza a virus 1 supporting sources ★☆☆☆☆
Trypanosomes 1 supporting sources ★☆☆☆☆

Aspergillus niger

  1. BMC plant biology

Cancer

  1. Fitoterapia

Influenza a virus

  1. Journal of ethnopharmacology

Trypanosomes

  1. Zeitschrift fur Naturforschung. C, Journal of biosciences

Preparations

Acokanthera schimperi has 7 reported preparations identified across 0 scientific publications and several other databases. The most consistently reported preparations include 80% methanol extracts, 80% methanolic extracts, Crude extracts, Hydroalcoholic extracts, absolute methanol.

Preparations reported for Acokanthera schimperi
Preparation Supporting sources Consensus
80% methanol extracts 1 supporting sources ★☆☆☆☆
80% methanolic extracts 1 supporting sources ★☆☆☆☆
Crude extracts 1 supporting sources ★☆☆☆☆
Hydroalcoholic extracts 1 supporting sources ★☆☆☆☆
Absolute methanol 1 supporting sources ★☆☆☆☆
Essential oils 1 supporting sources ★☆☆☆☆
Water 1 supporting sources ★☆☆☆☆

80% methanol extracts

  1. Molecules (Basel, Switzerland)

80% methanolic extracts

  1. Journal of ethnopharmacology

Crude extracts

  1. BMC plant biology

Hydroalcoholic extracts

  1. Journal of ethnopharmacology

Absolute methanol

  1. Asian Pacific journal of tropical biomedicine

Essential oils

  1. BMC plant biology

Water

  1. Asian Pacific journal of tropical biomedicine