Achnatherum inebrians
Achnatherum inebrians · Accepted scientific name
Scientific literature: Very Sparse (1 studies) · ★☆☆☆☆
Achnatherum inebrians is a botanical species that has garnered significant scientific interest due to its diverse chemical profile. Research into this plant has focused on the isolation of specific bioactive compounds, most notably the chemical deoxyvasicinone. To study these constituents, researchers have utilized various preparation methods involving different polar extraction parts and specialized solvent extracts. Further refinement through the creation of distinct fractions allows for a more detailed analysis of its pharmacological properties. Ultimately, these investigations aim to characterize the potent cytotoxic activities inherent within the plant's chemical makeup.
- Synonyms
- Stipa Inebrians
- Common names
- Not available
- Family
- Poaceae
- Distribution
- Not available
- Plant Parts
- Not available
Classification
Synonyms
Achnatherum inebrians is a notable grass species that is often recognized by its alternative botanical classification. In various scientific records, this plant is also identified by the synonym Stipa inebrians. Understanding these overlapping names is essential for researchers tracking the plant's distribution and biological properties. This nomenclatural link ensures that data remains consistent across different databases and historical texts. Consequently, recognizing both names allows for a more accurate study of this specific botanical entity.
Sources: The World Checklist of Vascular Plants (WCVP)
Taxonomy
Achnatherum inebrians is a unique biological specimen that belongs to the kingdom Plantae. Within this vast kingdom, the plant is classified under the class Equisetopsida. It further falls into the specific order Poales, showcasing its evolutionary connections. As a member of the family Poaceae, it shares characteristics common to many widespread grasses. Finally, its scientific identity is solidified by its placement within the genus Achnatherum.
| Rank | Classification |
|---|---|
| Kingdom | Plantae |
| Phylum | Streptophyta |
| Class | Equisetopsida |
| Subclass | Magnoliidae |
| Order | Poales |
| Family | Poaceae |
| Genus | Achnatherum |
Sources: The World Checklist of Vascular Plants (WCVP)
Distribution
Geographic Regions
Achnatherum inebrians is a resilient plant species primarily found within the Asia-Temperate region. Its distribution is heavily concentrated across various provinces in China, showcasing a broad ecological range. Specifically, it can be identified throughout the North-Central and South-Central territories of the country. The species also thrives in the expansive landscapes of Inner Mongolia and the high altitudes of Qinghai. Furthermore, its presence extends into the unique environmental conditions found within Tibet.
Sources: The World Checklist of Vascular Plants (WCVP)
Identification
Morphology
Achnatherum inebrians is a self-supporting herb that grows upright in its natural habitat. This distinct growth form allows the plant to maintain its structure without the need for external support.
Sources: Global Inventory of Floras and Traits (GIFT)
Biological Activities
Achnatherum inebrians has demonstrated significant cytotoxic activity through recent research involving advanced screening techniques. By utilizing surface plasmon resonance and chromatography, scientists successfully identified specific bioactive components within this medicinal herb. A key compound discovered during this process is deoxyvasicinone, which exhibits a high affinity for the α-Mannosidase target. This specific component proved highly effective at inhibiting the proliferation of various human cancer cell lines, including hepatoma, breast, and lung cancer cells. Ultimately, these findings highlight the potential of A. inebrians as a valuable source for developing potent anti-cancer treatments.
Compounds
Achnatherum inebrians has been identified as a significant source of bioactive compounds through advanced directional screening techniques. By utilizing a combination of surface plasmon resonance and chromatography, researchers successfully isolated several novel compounds from this medicinal herb. Among these findings, deoxyvasicinone emerged as a standout component due to its exceptionally high binding affinity to the α-Mannosidase target. This specific compound demonstrated remarkable cytotoxic potential by effectively inhibiting the proliferation of various human cancer cell lines. Ultimately, the isolation of deoxyvasicinone from A. inebrians highlights the plant's promising role in the development of new anti-cancer therapies.
Conditions
Achnatherum inebrians contains deoxyvasicinone, an active component that demonstrates significant cytotoxic activity against various human cancer cell lines. This medicinal herb effectively inhibits the proliferation of human breast cancer cells, specifically the MCF7 line. It also shows potent effects in treating human hepatoma cells, such as the HepG2 line. Furthermore, the plant provides a powerful treatment for human lung cancer cells, specifically the HCC827 line. The inhibitory impact on these HCC827 lung cancer cells was even noted to be stronger than the positive drug gefitinib.
Preparations
Achnatherum inebrians is prepared as different polar extraction parts to facilitate the screening of its bioactive components. The plant is also prepared as different solvents extracts during the directional identification process. Furthermore, Achnatherum inebrians is prepared as fractions to allow for precise orientation and isolation of active substances. These specific preparation methods are utilized alongside surface plasmon resonance and chromatography to target α-Mannosidase. By using these different extraction parts, solvent extracts, and fractions, researchers can effectively isolate potential cytotoxic compounds.