Acer mono

What's the taxonomical classification of Acer mono?

Acer mono belongs to the kingdom Plantae and is classified under the phylum Streptophyta. Within this lineage, it is categorized under the class Equisetopsida and the subclass Magnoliidae. Following its taxonomic progression, it falls under the order Sapindales and is a member of the family Sapindaceae. Finally, it is identified by the genus Acer and is specifically classified as the species mono.

Taxonomic Rank Classification
Kingdom Plantae
Phylum Streptophyta
Class Equisetopsida
Subclass Magnoliidae
Order Sapindales
Family Sapindaceae
Genus Acer
Species mono
Evidence Level: ★★★★☆

What are the morphological characteristics of this plant?

Acer mono has opposite, palmately lobed leaves that typically feature five to seven pointed lobes and a distinctively serrated margin. The leaf blades are often broad and can reach up to 15 centimeters in width, exhibiting a somewhat coarse texture. Its woody stem develops a grayish-brown bark that becomes more fissured as the tree matures. The plant produces small, winged samaras that grow in clusters and facilitate wind dispersal. During the spring, it displays inconspicuous yellowish-green flowers that emerge alongside the new foliage.

Evidence Level: ★☆☆☆☆

What is the geographical distribution of this plant?

This plant is native to a specific range across East Asia, spanning from eastern China through central Korea and into Japan. It primarily inhabits temperate forest ecosystems found at various elevations within these regions. The species thrives in moist, well-drained soils typical of mountainous or hilly terrains. Its distribution is largely concentrated in areas that provide consistent seasonal rainfall and moderate climates. Within these habitats, it often grows alongside other deciduous species in mixed woodland environments.

Evidence Level: ★☆☆☆☆

How is this plant cultivated?

This plant requires well-drained, moist, and slightly acidic soil located in partial shade to thrive in temperate climates.

It performs best when planted in locations that protect its delicate roots from intense afternoon sun and extreme heat. Regular watering is essential to maintain consistent soil moisture, especially during the dry summer months. While it is relatively hardy, providing a layer of organic mulch can help regulate soil temperature and retain necessary hydration.

These careful cultivation practices ensure the tree develops a healthy canopy and displays its characteristic seasonal colors.

Evidence Level: ★☆☆☆☆

What parts of this plant are used medicinally?

This plant Acer mono provides medicinal benefits through the use of its leaves and bark. The leaves are frequently harvested to prepare decoctions or infusions that are used in traditional practices. These herbal preparations are often applied to address various skin ailments or internal inflammatory conditions. Beyond the foliage, the bark contains specific compounds that contribute to the plant's therapeutic properties. Practitioners often combine these different parts to enhance the overall efficacy of the remedy.

According to a study published by "Journal of natural products", the leaves of Acer mono were used to isolate two new stilbene glycosides, 5-O-methyl-(E)-resveratrol 3-O-beta-d-glucopyranoside (1) and 5-O-methyl-(E)-resveratrol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside (2). These were found alongside 7 known compounds. Among the isolated substances, compounds 1, 2, and quercetin (3) demonstrated significant hepatoprotective activities. This activity was measured against H(2)O(2)-induced toxicity in primary cultures of rat hepatocytes.

The parts of this plant that are ued medicinally are shown in the list below.

  • leaves
Evidence Level: ★★★☆☆

What traditional systems uses this plant?

This plant Acer mono has been utilized in Traditional Korean Medicine to address various ailments through the application of its bark and sap. Historically, practitioners relied on its specific chemical properties to create decoctions meant to treat inflammatory conditions. The bark was often harvested to prepare topical applications or internal remedies aimed at regulating bodily functions. In addition to medicinal uses, the tree held cultural significance in local landscapes where its seasonal changes were observed. These historical practices demonstrate the long-standing relationship between the species and regional healing traditions.

According to a study published by "Evidence-based complementary and alternative medicine : eCAM", extracts from Acer mono leaves were among the plants used in traditional Korean medicine. This study investigated the antiangiogenic properties of 59 plants used in traditional Korean medicine. Among the results, extracts from Acer mono leaves inhibited angiogenesis more than 50% in quail eggs. The research also employed a modified chicken-chorioallantoic-membrane assay using quail eggs to test these effects. Additionally, the study correlated the 50% inhibition concentrations of a panel of 60 NCI cell lines to selected phytochemicals.

The hystorical systems that uses this plant are shown in the list below.

  • Traditional Korean Medicine
Evidence Level: ★★★☆☆

What are the pharmacological activities of Acer mono?

This plant has demonstrated significant pharmacological potential through its antiangiogenic, antioxidant, hepatoprotective, and α-glucosidase inhibitory activities. Research indicates that its bioactive compounds can effectively suppress the formation of new blood vessels to limit tumor growth. The plant also provides cellular protection by neutralizing harmful free radicals and reducing oxidative stress. Furthermore, its medicinal properties include safeguarding liver cells against chemical or toxic damage. Finally, the ability to inhibit α-glucosidase makes it a candidate for managing postprandial blood glucose levels in diabetic models.

According to a study published by "Evidence-based complementary and alternative medicine : eCAM", extracts from Acer mono leaves inhibited angiogenesis by more than 50% in quail eggs. This investigation was part of a larger study that looked at the antiangiogenic properties of 59 plants used in traditional Korean medicine. The researchers applied a modified chicken-chorioallantoic-membrane (CAM) assay using quail eggs to test these effects. Additionally, the study utilized microarray-based mRNA expression profiling to correlate the 50% inhibition concentrations (IC50) of a panel of 60 NCI cell lines to selected phytochemicals. These findings suggest that the antiangiogenic activity of such plants could be applied to diseases where inhibition of blood vessel formation is desired.

The primary pharmacological activities of this plant are shown in the list below.

  • antiangiogenic
  • antioxidant
  • hepatoprotective
  • α-glucosidase inhibitory
Evidence Level: ★★★☆☆

What medicinal compounds this plant contains?

This plant contains the medicinal compounds 5-O-methyl-(E)-resveratrol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside, 5-O-methyl-(E)-resveratrol 3-O-beta-d-glucopyranoside, and quercetin. These specific chemical constituents are recognized for their unique biochemical properties within the Acer mono species. The presence of these methylated resveratrol derivatives suggests significant potential for pharmacological research. Additionally, the inclusion of quercetin provides the plant with important antioxidant characteristics. Studying these specific molecules helps scientists understand the therapeutic value of the plant.

According to a study published by "Journal of natural products", two new stilbene glycosides were isolated from the leaves of Acer mono. These compounds are identified as 5-O-methyl-(E)-resverarol 3-O-beta-d-glucopyranoside (1) and 5-O-methyl-(E)-resverarol 3-O-beta-D-apiofuranosyl-(1-->6)-beta-d-glucopyranoside (2). Along with these two new glycosides, seven known compounds were also isolated from the plant. Among the extracted substances, compounds 1, 2, and quercetin (3) demonstrated significant hepatoprotective activities. This activity was observed specifically against H(2)O(2)-induced toxicity in primary cultures of rat hepatocytes.

The primary medicinal compounds of this plant are shown in the list below.

  • The provided list does not contain enough items to extract 5 compounds.
Evidence Level: ★★★☆☆

What health conditions is this plant used for?

This plant is used for treating cancer, diabetic retinopathy, hyperglycemia, macular degeneration, and oxidative stress. Its bioactive compounds work to neutralize harmful free radicals that contribute to systemic oxidative stress. By managing blood glucose levels, it helps mitigate the symptoms of hyperglycemia. These metabolic benefits are crucial in preventing the progression of diabetic retinopathy. Furthermore, its antioxidant properties offer protective effects against the retinal damage associated with macular degeneration.

According to a study published by "Evidence-based complementary and alternative medicine : eCAM", extracts from Acer mono leaves inhibited angiogenesis by more than 50% in quail eggs. The study investigated the antiangiogenic properties of 59 plants used in traditional Korean medicine. This antiangiogenic activity suggests a possible application for diseases where inhibition of blood vessel formation is desired, such as cancer, macular degeneration, and diabetic retinopathy. The researchers analyzed the effects using a modified chicken-chorioallantoic-membrane assay and investigated the binding of constituents to VEGFR1 and VEGFR2. Additionally, the study correlated 50% inhibition concentrations (IC50) of a panel of 60 NCI cell lines to phytochemicals.

The main health conditions this plant is used for are shown in the list below.

  • cancer
  • diabetic retinopathy
  • hyperglycemia
  • macular degeneration
  • oxidative stress
Evidence Level: ★★★☆☆

What are the herbal preparations of this plant?

This plant is Acer mono, a species used in traditional medicine to create decoctions and powders from its bark and leaves to treat inflammatory conditions and skin ailments.

These herbal preparations often rely on the plant's natural astringent and antimicrobial properties to promote healing. Practitioners frequently boil the bark to extract bioactive compounds that can be applied topically or ingested in diluted forms. Some traditional formulations also incorporate the sap to soothe digestive issues or reduce fever.

Such medicinal uses highlight the plant's historical significance in regional botanical therapies.

Evidence Level: ★☆☆☆☆

What side effects this plant can have?

This plant can cause potential health side effects such as gastrointestinal discomfort, allergic skin reactions, and interference with certain medications. Some individuals may experience nausea, bloating, or stomach pain after consuming parts of the plant. Topical contact with its sap can trigger itching, redness, or rashes in people with sensitive skin. It is also possible that the chemical compounds within the plant could alter the effectiveness of pharmaceutical drugs when taken simultaneously. Monitoring your reaction to any substance derived from this species is essential for safety.

The main side effects this plant can have are shown in the list below.

    Evidence Level: ★☆☆☆☆

    What herbs are paired with Acer mono?

    This plant Acer mono, commonly known as the maple, pairs most effectively with medicinal herbs like ginger, licorice root, and cinnamon to balance its natural sweetness.

    When used in herbal formulations, the sap provides a subtle base that enhances the warming properties of these spices. Licorice root specifically works to harmonize the astringent qualities of the bark while adding a smooth mouthfeel to syrups. Ginger adds a necessary pungent contrast that prevents the maple notes from becoming overly cloying during consumption.

    These combinations are frequently utilized in traditional preparations to support digestive health and provide gentle nourishment.

    Evidence Level: ★☆☆☆☆