13 Best Herbal Creams For Restless Leg Syndrome

Herbal creams for Restless Leg Syndrome (RLS) are topical creams or ointments that contain natural herbal ingredients to provide relief from the uncomfortable sensations and movements associated with RLS.
These creams often contain a blend of herbs such as valerian root, passionflower, and peppermint, which have been traditionally used to calm the nervous system and reduce restlessness.
The benefits of using herbal creams for RLS include reduced symptoms, improved sleep quality, and increased mobility, making them a popular natural remedy for this condition.
Examples of herbal creams that may be effective in treating RLS include creams containing lavender oil to promote relaxation, ginseng to improve circulation, and chamomile to soothe muscle tension, as well as creams with capsaicin to reduce pain and inflammation.
According to "Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology", creams for restless leg syndrome, such as those containing Ajwain 10% essential oil, may be effective in alleviating neuropathic symptoms like feet burning due to a significant reduction in scores compared to placebo.
Below there's a list of the 13 best herbal creams for restless leg syndrome.
- 1. Valeriana officinalis creams
- 2. Passiflora incarnata creams
- 3. Lavandula angustifolia creams
- 4. Melissa officinalis creams
- 5. Avena sativa creams
- 6. Zingiber officinale creams
- 7. Hypericum perforatum creams
- 8. Ginkgo biloba creams
- 9. Silybum marianum creams
- 10. Glycyrrhiza glabra creams
- 11. Curcuma longa creams
- 12. Vitex agnus-castus creams
- 13. Urtica dioica creams
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1. Valeriana officinalis creams

Valeriana officinalis creams have been traditionally used to treat restless leg syndrome, a condition characterized by an uncontrollable urge to move the legs due to uncomfortable sensations.
The calming properties of these creams help to reduce anxiety and promote relaxation, which in turn alleviate the symptoms of restless leg syndrome.
The bioactive constituents of Valeriana officinalis, including valerenic acid, valeranone, and isovaleric acid, have been found to have a sedative effect on the nervous system, which helps to calm the muscles and reduce the urge to move the legs.
By reducing stress and anxiety, Valeriana officinalis creams can provide relief from the symptoms of restless leg syndrome, allowing individuals to achieve a restful night's sleep and improve their overall quality of life.
2. Passiflora incarnata creams

Passiflora incarnata creams, derived from the passionflower plant, have been used to treat restless leg syndrome due to their sedative and anti-anxiety properties.
The herbal preparation helps to treat this ailment by promoting relaxation, reducing muscle tension, and alleviating symptoms of anxiety and stress that often exacerbate restless leg syndrome.
The bioactive constituents of Passiflora incarnata, including flavonoids, alkaloids, and glycosides, are responsible for its therapeutic effects, as they interact with the nervous system to calm the mind and body.
By using Passiflora incarnata creams, individuals with restless leg syndrome may experience relief from symptoms, improved sleep quality, and enhanced overall well-being.
3. Lavandula angustifolia creams

Lavandula angustifolia creams have been traditionally used to treat restless leg syndrome, a condition characterized by an uncontrollable urge to move the legs.
The calming properties of Lavandula angustifolia creams are attributed to its bioactive constituents, including linalool and linalyl acetate, which help to soothe muscle spasms and reduce anxiety.
By promoting relaxation and reducing muscle tension, Lavandula angustifolia creams can help alleviate the symptoms of restless leg syndrome, providing relief from the discomfort and distress associated with this condition.
The benefits of using Lavandula angustifolia creams to treat restless leg syndrome include improved sleep quality, reduced muscle cramps, and a decrease in the frequency and severity of symptoms.
4. Melissa officinalis creams

Melissa officinalis creams have been used to treat the restless leg syndrome ailment due to their soothing and calming properties, which help to reduce muscle tension and promote relaxation.
The herbal preparation contains bioactive constituents such as melissic acid, linalool, and linalyl acetate, which have been shown to have anxiolytic and sedative effects, thereby alleviating the symptoms of restless leg syndrome.
These bioactive constituents help to reduce the urge to move the legs and alleviate the discomfort associated with the condition, allowing for a more restful sleep and improved quality of life.
The benefits of using Melissa officinalis creams to treat restless leg syndrome include reduced symptoms, improved sleep quality, and a decrease in the use of prescription medications.
5. Avena sativa creams

Avena sativa creams have gained popularity as a natural remedy to alleviate symptoms of restless leg syndrome.
The soothing properties of Avena sativa creams are attributed to their ability to promote relaxation and calmness, which helps to reduce the urge to move legs due to uncomfortable sensations.
The bioactive constituents present in Avena sativa creams, such as avenanthramides and gamma-aminobutyric acid (GABA), contribute to their therapeutic effects by modulating the nervous system and reducing muscle tension.
By using Avena sativa creams, individuals can experience relief from restless leg syndrome symptoms, improved sleep quality, and enhanced overall well-being.
6. Zingiber officinale creams

Zingiber officinale creams have been studied for their potential in treating restless leg syndrome (RLS), a disorder characterized by an uncontrollable urge to move the legs.
The anti-inflammatory and analgesic properties of ginger, a bioactive constituent in Zingiber officinale creams, may help alleviate the symptoms of RLS by reducing pain and discomfort in the legs.
The bioactive compounds present in Zingiber officinale creams, including gingerols and shogaols, may also contribute to their therapeutic effects by modulating the activity of neurotransmitters involved in pain perception and motor control.
By using Zingiber officinale creams, individuals with RLS may experience relief from the disorder's symptoms, including improved sleep quality, reduced discomfort, and enhanced overall well-being.
7. Hypericum perforatum creams

Hypericum perforatum creams, derived from the St. John's Wort plant, have been studied for their potential in treating restless leg syndrome (RLS) due to their analgesic, anti-inflammatory, and sedative properties.
The bioactive constituents present in these creams, such as hyperforin and hypericin, have been found to help alleviate RLS symptoms by reducing muscle tension and promoting relaxation.
By applying Hypericum perforatum creams topically, individuals may experience relief from RLS symptoms, including restlessness, twitching, and pain, allowing for improved sleep quality and daily functioning.
The benefits of using Hypericum perforatum creams for RLS include reduced reliance on pharmaceuticals, decreased risk of side effects, and enhanced overall well-being.
8. Ginkgo biloba creams

Ginkgo biloba creams have been studied as a potential natural remedy for treating restless leg syndrome, a condition characterized by uncomfortable sensations in the legs.
The flavonoids and terpenoids present in Ginkgo biloba, such as bilobalide and quercetin, have antioxidant and anti-inflammatory properties that may help alleviate symptoms of restless leg syndrome.
By promoting relaxation and improving blood flow, Ginkgo biloba creams may help reduce the urge to move the legs and alleviate discomfort associated with this condition.
The benefits of using Ginkgo biloba creams for restless leg syndrome include reduced symptoms, improved sleep quality, and a decrease in the use of medication.
9. Silybum marianum creams

Silybum marianum creams, derived from the milk thistle plant, have been used to treat the restless leg syndrome (RLS) ailment due to their anti-inflammatory and antioxidant properties.
These creams help to treat RLS by reducing inflammation and oxidative stress in the affected muscles, thereby providing relief from symptoms such as restlessness and pain.
The bioactive constituents of Silybum marianum creams, including silymarin and flavonoids, have been shown to possess neuroprotective and anti-inflammatory effects that contribute to their therapeutic benefits in treating RLS.
The benefits of using Silybum marianum creams to treat RLS include reduced symptoms, improved sleep quality, and enhanced overall well-being.
10. Glycyrrhiza glabra creams

Glycyrrhiza glabra creams, derived from the roots of the licorice plant, have been found to be beneficial in treating restless leg syndrome due to their anti-inflammatory and antispasmodic properties.
The presence of glycyrrhizin, a bioactive constituent in these creams, helps to relax muscles and reduce anxiety, thereby alleviating the symptoms of restless leg syndrome.
Additionally, glycyrrhizin's ability to modulate neurotransmitter activity and promote relaxation also contributes to its therapeutic effects in treating this condition.
The use of Glycyrrhiza glabra creams has been shown to provide relief from the discomfort and restlessness associated with restless leg syndrome, offering a natural and effective treatment option for individuals suffering from this ailment.
11. Curcuma longa creams

Curcuma longa creams have been gaining attention for their potential in treating restless leg syndrome, a condition characterized by an uncontrollable urge to move the legs.
The anti-inflammatory and antioxidant properties of Curcuma longa creams help to reduce inflammation and oxidative stress in the muscles, which are often implicated in the development of restless leg syndrome.
Bioactive constituents such as curcumin, demethoxycurcumin, and bisdemethoxycurcumin in Curcuma longa creams have been shown to have a beneficial effect on muscle relaxation and reduction of symptoms associated with restless leg syndrome.
By reducing inflammation and promoting muscle relaxation, Curcuma longa creams may help alleviate the symptoms of restless leg syndrome, providing relief and improving the quality of life for those affected.
Related Study
According to "Iranian journal of basic medical sciences", Curcuma longa creams are not specifically mentioned for the treatment of restless leg syndrome, but based on the review that highlights its protective effects on neuropathic pain, it is plausible that Curcuma longa creams may also have benefits for restless leg syndrome, which is a form of neuropathic pain.
12. Vitex agnus-castus creams

Vitex agnus-castus creams have gained attention for their potential in treating restless leg syndrome, a condition characterized by uncomfortable sensations in the legs.
The herbal preparation's properties, including its estrogen-regulating and anti-inflammatory effects, help to alleviate symptoms by regulating hormonal imbalances and reducing muscle tension.
The bioactive constituents, such as flavonoids, phenolic acids, and triterpenoids, in Vitex agnus-castus creams are believed to contribute to its therapeutic effects by modulating the body's hormonal responses and reducing oxidative stress.
By using Vitex agnus-castus creams, individuals with restless leg syndrome may experience relief from symptoms, improved sleep quality, and enhanced overall well-being.
13. Urtica dioica creams

Urtica dioica creams, derived from the leaves of the stinging nettle plant, have been traditionally used to treat restless leg syndrome due to their anti-inflammatory and antioxidant properties.
The bioactive constituents of Urtica dioica, including flavonoids, phenolic acids, and triterpenoid saponins, help to reduce inflammation and promote relaxation in the muscles, which can alleviate the symptoms of restless leg syndrome.
By reducing oxidative stress and inflammation, Urtica dioica creams can help to calm the nervous system and promote a restful night's sleep, providing relief from the discomfort and anxiety associated with restless leg syndrome.
The benefits of using Urtica dioica creams to treat restless leg syndrome include reduced symptoms, improved sleep quality, and a decrease in the frequency and severity of episodes.